Drug profile · INN
vepdegestrant
VEPPANU
vepdegestrant (VEPPANU) is an FDA-listed pharmaceutical active ingredient. Route of administration: oral. Current US regulatory status: approved.
Drug details — vepdegestrant
- US status
- approved
- Class
- —
- Route
- ORAL
- Patents
- 0
- Programs
- 3
- Data quality
- 0.84
Quick answer
vepdegestrant (VEPPANU) is an FDA-listed pharmaceutical active ingredient. Route of administration: oral. Current US regulatory status: approved.
Key facts
Approval history
| Authority | Status | Date |
|---|---|---|
| FDA | approved | — |
Recent coverage
FDA approves Vepdegestrant (Veppanu) for ESR1-mutated breast cancer
The FDA approved vepdegestrant (Veppanu) on May 1, 2026 for adults with ER-positive, HER2-negative, ESR1-mutated advanced or metastatic breast cancer after endocrine therapy. For BD teams and investors, the key read-through is a new catalyst tied to an FDA-labeled oral protein degrader and a clearly defined biomarker-selected population.
Rigel Pharmaceuticals Licenses FDA-Approved Breast Cancer Drug VEPPANU
Rigel Pharmaceuticals has successfully licensed VEPPANU, an FDA-approved drug for breast cancer, marking a significant milestone in its growth strategy.
Arvinas VEPPANU (Vepdegestrant) Receives FDA Approval as First PROTAC Drug for ESR1-Mutated Breast Cancer
Arvinas' VEPPANU becomes the first FDA-approved PROTAC drug for ESR1-mutated, ER+/HER2- advanced breast cancer, marking a breakthrough in protein degradation therapy.
FDA Approval for Pfizer's Breast Cancer Drug: Vepdegestrant
The FDA has granted approval for Pfizer and Arvinas' novel breast cancer drug, vepdegestrant. This marks a significant new treatment option for patients with advanced or metastatic HR-positive, HER2-negative breast cancer who have exhausted prior endocrine therapies.
Pipeline programs
Frequently asked questions
What is vepdegestrant?
vepdegestrant (VEPPANU) is an FDA-listed pharmaceutical active ingredient. Route of administration: oral. Current US regulatory status: approved.
What is the brand name for vepdegestrant?
VEPPANU is a marketed brand name for vepdegestrant. Check FDA Drugs@FDA for the current US label holder and prescribing information.
What is the US approval status of vepdegestrant?
vepdegestrant has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.