Wednesday, July 8, 2026

Drug profile · INN

ustekinumab

ustekinumab (STELARA) is a interleukin-23 inhibitor. Associated with Janssen-Cilag Pty Ltd. Route of administration: injection. Current US regulatory status: approved.

FDA: approved EMA: approved TGA: approved PMDA: approved Antineoplastic and immunomodulating agents (L04) L04AC05
US status approved
Patents linked 20
Pipeline programs 12
News articles 3
Drug details — ustekinumab
US status
approved
Class
Antineoplastic and immunomodulating agents (L04)
Route
INJECTION
Patents
20
Programs
12
Data quality
0.84

Quick answer

ustekinumab (STELARA) is a interleukin-23 inhibitor. Associated with Janssen-Cilag Pty Ltd. Route of administration: injection. Current US regulatory status: approved.

Key facts

INN ustekinumab
Brand STELARA
Mechanism Interleukin-23 inhibitor
Target Interleukin-12
Therapeutic class Antineoplastic and immunomodulating agents (L04)
Route INJECTION
Formulation INJECTABLE
ATC code L04AC05

Mechanism of action

Interleukin-23 inhibitor

Primary target: Interleukin-12

Approval history

Authority Status Date
FDA approved
EMA approved
TGA approved
PMDA approved

Recent coverage

Pipeline programs

  1. 77242113PSA3001 Phase 3 · Janssen-Cilag International N.V · Active Psoriatic Arthritis
  2. 77242113PSO3006 Phase 3 · Janssen-Cilag International N.V · Moderate to Severe Plaque Psoriasis
  3. CNTO1275JPA3001 Phase 3 · Janssen-Cilag International N.V · Juvenile psoriatic arthritis
  4. CNTO1959CRD3001 Phase 3 · Janssen-Cilag International N.V · Moderately to Severely Active Crohn's Disease
  5. PS0021 Phase 3 · Anaxis Pharma · Moderate to Severe Plaque Psoriasis
  6. Ustekinumab Phase 3 · First People's Hospital · Crohn Disease
  7. Ustekinumab Dose Based on BSA and Body Weight Phase 3 · Janssen Cilag International · Colitis, Ulcerative
  8. 1425-0003 Phase 2 · Boehringer Ingelheim · Crohn`s Disease (CD)

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. axitinib Antineoplastic and immunomodulating agents (L01)
  6. azacitidine Antineoplastic and immunomodulating agents (L01)
  1. US 12268831

    Swallowable drug delivery device and methods of drug delivery

    Expires Mon Apr 03 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 12263325

    Device, system and methods for the oral delivery of therapeutic compounds

    Expires Mon Mar 27 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 12214019

    Pharmaceutical compositions and methods for fabrication of solid masses comprising polypeptides and/or proteins

    Expires Mon Jan 30 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 12201721

    Clotting factor preparations for delivery into tissue of the intestinal tract using a swallowable drug delivery device

    Expires Mon Jan 16 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 12128133

    Ingestible device with expandable enclosure

    Expires Mon Oct 24 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 11826464

    Clotting factor preparations for delivery into tissue of the intestinal tract using a swallowable drug delivery device

    Expires Mon Nov 23 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 11814427

    Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device

    Expires Mon Nov 09 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 11806504

    Device, system and methods for the oral delivery of therapeutic compounds

    Expires Mon Nov 02 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 11771879

    Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device

    Expires Mon Sep 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 11718665

    Pharmaceutical compositions and methods for fabrication of solid masses comprising polypeptides and/or proteins

    Expires Mon Aug 03 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 11684761

    Preparation comprising exanatide for delivery into a lumen of the intestinal tract

    Expires Mon Jun 22 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 11638690

    Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device

    Expires Mon Apr 27 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 11555068

    Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device

    Expires Mon Jan 12 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 11464737

    Clotting factor preparations for delivery into tissue of the intestinal tract using a swallowable drug delivery device

    Expires Mon Oct 06 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 11376405

    Therapeutic agent preparations into a lumen of the intestinal tract using a swallowable drug delivery device

    Expires Mon Jun 30 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 11338118

    Swallowable drug delivery device and methods of drug delivery

    Expires Mon May 19 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 11304895

    Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device

    Expires Mon Apr 14 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 11304993

    Pharmaceutical compositions and methods for fabrication of solid masses comprising polypeptides and/or proteins

    Expires Mon Apr 14 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 11253686

    Swallowable drug delivery device and methods of drug delivery

    Expires Mon Feb 17 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 11229684

    Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device

    Expires Mon Jan 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is ustekinumab?

ustekinumab (STELARA) is a interleukin-23 inhibitor. Associated with Janssen-Cilag Pty Ltd. Route of administration: injection. Current US regulatory status: approved.

What is the brand name for ustekinumab?

STELARA is a marketed brand name for ustekinumab. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of ustekinumab?

ustekinumab has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.