Friday, July 10, 2026

Drug profile · INN

tremelimumab

tremelimumab (IMJUDO) is a cytotoxic t-lymphocyte protein 4 inhibitor. Associated with AstraZeneca.

EMA: approved TGA: approved Antineoplastic and immunomodulating agents (L01) L01FX20
Patents linked 0
Pipeline programs 24
News articles 1
Drug details — tremelimumab

Quick answer

tremelimumab (IMJUDO) is a cytotoxic t-lymphocyte protein 4 inhibitor. Associated with AstraZeneca.

Key facts

INN tremelimumab
Brand IMJUDO
Mechanism Cytotoxic T-lymphocyte protein 4 inhibitor
Target Cytotoxic T-lymphocyte protein 4
Therapeutic class Antineoplastic and immunomodulating agents (L01)
ATC code L01FX20
Originator AstraZeneca

Mechanism of action

Cytotoxic T-lymphocyte protein 4 inhibitor

Primary target: Cytotoxic T-lymphocyte protein 4

Approval history

Authority Status Date
EMA approved
TGA approved

Recent coverage

Pipeline programs

  1. CSET N° 2023/3729 Phase 3 · George Institute for · Synchronous oligometastatic non-small cell lung cancer (NSCL
  2. D419CC00002 Phase 3 · AstraZeneca · Advanced hepatocellular carcinoma (HCC)
  3. D7029C00001 Phase 3 · AstraZeneca · Advanced Hepatocellular Carcinoma
  4. D910PC00001 - Volga Phase 3 · AstraZeneca · Bladder Cancer
  5. D910VC00001 Phase 3 · AstraZeneca · Locoregional Hepatocellular Carcinoma (HCC)
  6. D933QC00001 Phase 3 · AstraZeneca · Patients with Limited Stage Small-Cell Lung Cancer (LS-SCLC)
  7. D933SC00001 Phase 3 · AstraZeneca · Patients with Unresectable Locally Advanced or Metastatic Ur
  8. DANUBE/D419BC00001 Phase 3 · AstraZeneca · Adult patients (age ≥18 years) with histologically or cytolo

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. axitinib Antineoplastic and immunomodulating agents (L01)
  6. azacitidine Antineoplastic and immunomodulating agents (L01)

Frequently asked questions

What is tremelimumab?

tremelimumab (IMJUDO) is a cytotoxic t-lymphocyte protein 4 inhibitor. Associated with AstraZeneca.

What is the brand name for tremelimumab?

IMJUDO is a marketed brand name for tremelimumab. Check FDA Drugs@FDA for the current US label holder and prescribing information.