Saturday, July 11, 2026

Drug profile · INN

topotecan

topotecan (HYCAMTIN) is a dna topoisomerase i, mitochondrial inhibitor. Associated with Accord Healthcare Pty..

EMA: approved TGA: approved NMPA: clinical trials Antineoplastic and immunomodulating agents (L01) L01CE01
Patents linked 0
Pipeline programs 5
News articles 0
Drug details — topotecan
Class
Antineoplastic and immunomodulating agents (L01)
Route
Patents
0
Programs
5
Data quality
0.89

Quick answer

topotecan (HYCAMTIN) is a dna topoisomerase i, mitochondrial inhibitor. Associated with Accord Healthcare Pty..

Key facts

INN topotecan
Brand HYCAMTIN
Mechanism DNA topoisomerase I, mitochondrial inhibitor
Therapeutic class Antineoplastic and immunomodulating agents (L01)
ATC code L01CE01

Mechanism of action

DNA topoisomerase I, mitochondrial inhibitor

Approval history

Authority Status Date
EMA approved
TGA approved
NMPA clinical trials

Pipeline programs

  1. 223674 Phase 3 · GSK Glaxo Smith · Neoplasms, Lung
  2. DS7300-188 Phase 3 · Daiichi Sankyo US · Small Cell Lung Cancer (SCLC)
  3. GCO-003 TARLANEC Phase 3 · CERo Therapeutics · Advanced pulmonary or gastroenteropancreatic poorly differen
  4. IC 2019-05 Phase 2 · George Institute for · Ocular conservative treatment for retinoblastoma
  5. Intravitreal aflibercept injection Approved · Regeneron UK · Macular Degeneration

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. axitinib Antineoplastic and immunomodulating agents (L01)
  6. azacitidine Antineoplastic and immunomodulating agents (L01)

Frequently asked questions

What is topotecan?

topotecan (HYCAMTIN) is a dna topoisomerase i, mitochondrial inhibitor. Associated with Accord Healthcare Pty..

What is the brand name for topotecan?

HYCAMTIN is a marketed brand name for topotecan. Check FDA Drugs@FDA for the current US label holder and prescribing information.