Drug profile · INN
topiramate
APO-TOPIRAMATE
topiramate (APO-TOPIRAMATE) is a gaba-a receptor; anion channel positive modulator. Associated with Alphapharm Pty Ltd. Route of administration: oral. Current US regulatory status: approved.
Drug details — topiramate
- US status
- approved
- Class
- —
- Route
- ORAL
- Patents
- 20
- Programs
- 25
- Data quality
- 0.89
Quick answer
topiramate (APO-TOPIRAMATE) is a gaba-a receptor; anion channel positive modulator. Associated with Alphapharm Pty Ltd. Route of administration: oral. Current US regulatory status: approved.
Key facts
Mechanism of action
GABA-A receptor; anion channel positive modulator
Primary target: Carbonic anhydrase 2
Approval history
| Authority | Status | Date |
|---|---|---|
| FDA | approved | — |
| TGA | approved | — |
| PMDA | approved | — |
Pipeline programs
Related & competitor drugs
Related patents
-
US 12180251
Nucleic acids encoding peptides that block binding of a2d-1 to glutamate receptors for treating diseases and disorders
granted -
US 11969470
Topiramate compositions and methods of making and using the same
granted -
US 11787839
Targeting α2δ-1-bound glutamate receptors for treating diseases and disorders
granted -
US 11447453
Metabotropic glutamate receptor negative allosteric modulators (NAMs) and uses thereof
granted -
US 11071787
Topiramate compositions and methods of making and using the same
granted -
US 10597367
Metabotropic glutamate receptor negative allosteric modulators (NAMs) and uses thereof
granted -
US 10398668
Glutamate treatment of cardiovascular disorders
granted -
US 10377695
Metabotropic glutamate receptor positive allosteric modulators (PAMS) and uses thereof
granted -
US 10314790
Sustained-release formulations of topiramate
granted -
US 9765091
Tetrahydropyrazolo [3,4-b] azepine derivatives and their use as allosteric modulators of metabotropic glutamate receptors
granted -
US 9744137
Topiramate compositions and methods of enhancing its bioavailability
granted -
US 9622983
Sustained-release formulations of topiramate
granted -
US 9555004
Sustained-release formulations of topiramate
granted -
US 9549940
Sustained-release formulations of topiramate
granted -
US 9073907
Thiazoles derivatives and their use as positive allosteric modulators of metabotropic glutamate receptors
granted -
US 8992989
Sustained-release formulations of topiramate
granted -
US 8889191
Sustained-release formulations of topiramate
granted -
US 8883826
Alkynyl derivatives as modulators of metabotropic glutamate receptors
granted -
US 8877248
Sustained-release formulations of topiramate
granted -
US 8697744
Substituted 5,6-dihydro-4H-thiazolo[4,5-E]indazoles and their use as positive allosteric modulators of metabotropic glutamate receptors
granted
Frequently asked questions
What is topiramate?
topiramate (APO-TOPIRAMATE) is a gaba-a receptor; anion channel positive modulator. Associated with Alphapharm Pty Ltd. Route of administration: oral. Current US regulatory status: approved.
What is the brand name for topiramate?
APO-TOPIRAMATE is a marketed brand name for topiramate. Check FDA Drugs@FDA for the current US label holder and prescribing information.
What is the US approval status of topiramate?
topiramate has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.