Wednesday, July 8, 2026

Drug profile · INN

tocilizumab

tocilizumab (ACTEMRA) is a interleukin-6 receptor alpha subunit inhibitor. Associated with Hoffmann-La Roche. Route of administration: injection. Current US regulatory status: approved.

FDA: approved EMA: approved TGA: approved PMDA: approved NMPA: clinical trials Antineoplastic and immunomodulating agents (L04) L04AC07
US status approved
Patents linked 0
Pipeline programs 78
News articles 0
Drug details — tocilizumab
US status
approved
Class
Antineoplastic and immunomodulating agents (L04)
Route
INJECTION
Patents
0
Programs
78
Data quality
0.84

Quick answer

tocilizumab (ACTEMRA) is a interleukin-6 receptor alpha subunit inhibitor. Associated with Hoffmann-La Roche. Route of administration: injection. Current US regulatory status: approved.

Key facts

INN tocilizumab
Brand ACTEMRA
Mechanism Interleukin-6 receptor alpha subunit inhibitor
Target Interleukin-6 receptor subunit alpha
Therapeutic class Antineoplastic and immunomodulating agents (L04)
Route INJECTION
Formulation INJECTABLE
ATC code L04AC07

Mechanism of action

Interleukin-6 receptor alpha subunit inhibitor

Primary target: Interleukin-6 receptor subunit alpha

Approval history

Authority Status Date
FDA approved
EMA approved
TGA approved
PMDA approved
NMPA clinical trials

Pipeline programs

  1. 1438-0011 Phase 3 · Boehringer Ingelheim · advanced or metastatic extrapulmonary neuroendocrine carcino
  2. 1438-0012 Phase 3 · Boehringer Ingelheim · small cell lung cancer
  3. 20200041 Phase 3 · Amgen · Extensive stage small cell lung cancer (ES-SCLC)
  4. 20230016 Phase 3 · Amgen · Limited-Stage Small-Cell Lung Cancer (LS SCLC)
  5. APHP200026 Phase 3 · PARItec · Patients with GPA and inadequate response to standard of car
  6. APHP220790 Phase 3 · PARItec · Chondrocalcinosis
  7. APHP220797 Phase 3 · PARItec · Sickle cell disease
  8. CA088-1007 Phase 3 · Celgene · Relapsed or Refractory and Lenalidomide exposed Multiple Mye

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. axitinib Antineoplastic and immunomodulating agents (L01)
  6. azacitidine Antineoplastic and immunomodulating agents (L01)

Frequently asked questions

What is tocilizumab?

tocilizumab (ACTEMRA) is a interleukin-6 receptor alpha subunit inhibitor. Associated with Hoffmann-La Roche. Route of administration: injection. Current US regulatory status: approved.

What is the brand name for tocilizumab?

ACTEMRA is a marketed brand name for tocilizumab. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of tocilizumab?

tocilizumab has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.