Wednesday, July 8, 2026

Drug profile · INN

ticagrelor

ticagrelor (ARX-TICAGRELOR) is a purinergic receptor p2y12 negative allosteric modulator. Associated with AstraZeneca. Route of administration: oral. Current US regulatory status: approved.

FDA: approved EMA: approved TGA: approved NMPA: clinical trials Blood and blood forming organs (B01) B01AC24
US status approved
Patents linked 1
Pipeline programs 24
News articles 0
Drug details — ticagrelor
US status
approved
Class
Blood and blood forming organs (B01)
Route
ORAL
Patents
1
Programs
24
Data quality
0.89

Quick answer

ticagrelor (ARX-TICAGRELOR) is a purinergic receptor p2y12 negative allosteric modulator. Associated with AstraZeneca. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN ticagrelor
Brand ARX-TICAGRELOR
Mechanism Purinergic receptor P2Y12 negative allosteric modulator
Target P2Y purinoceptor 12
Therapeutic class Blood and blood forming organs (B01)
Route ORAL
Formulation TABLET
ATC code B01AC24
Originator AstraZeneca

Mechanism of action

Purinergic receptor P2Y12 negative allosteric modulator

Primary target: P2Y purinoceptor 12

Approval history

Authority Status Date
FDA approved
EMA approved
TGA approved
NMPA clinical trials

Pipeline programs

  1. De-escalation to ticagrelor 60 mg at day 30 Phase 3 · COLLEGIUM PHARMACEUTICAL · Non ST Segment Elevation Acute Coronary Syndrome
  2. Ticagrelor Phase 3 · AstraZeneca · Acute Coronary Syndrome
  3. Ticagrelor 90 mg Phase 3 · COLLEGIUM PHARMACEUTICAL · Myocardial Infarction
  4. Ticagrelor 90 mg Phase 3 · AstraZeneca · Myocardial Infarction
  5. Ticagrelor 90mg Phase 3 · COLLEGIUM PHARMACEUTICAL · STEMI
  6. Ticagrelor and Aspirin Phase 3 · Chinese Academy of · Stroke
  7. ticagrelor Phase 3 · First People's Hospital · Coronary Artery Disease
  8. D3560C00817 Phase 1 · AstraZeneca · Clinical trial healthy volunteer

Related & competitor drugs

  1. apixaban Blood and blood forming organs (B01)
  2. berotralstat Blood and blood forming organs (B06)
  3. bivalirudin Blood and blood forming organs (B01)
  4. c1 inhibitor (human) Blood and blood forming organs (B06)
  5. clopidogrel Blood and blood forming organs (B01)
  6. clopidogrel bisulfate Purinergic receptor P2Y12 antagonist
  1. US 11723873

    Oral dosage form of ticagrelor and preparation method thereof

    Expires Mon Aug 10 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is ticagrelor?

ticagrelor (ARX-TICAGRELOR) is a purinergic receptor p2y12 negative allosteric modulator. Associated with AstraZeneca. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for ticagrelor?

ARX-TICAGRELOR is a marketed brand name for ticagrelor. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of ticagrelor?

ticagrelor has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.