Wednesday, July 8, 2026

Drug profile · INN

tazemetostat hydrobromide

tazemetostat hydrobromide (TAZVERIK) is a histone-lysine n-methyltransferase ezh2 inhibitor. Route of administration: oral. Current US regulatory status: approved.

FDA: approved PMDA: approved
US status approved
Patents linked 0
Pipeline programs 2
News articles 0
Drug details — tazemetostat hydrobromide
US status
approved
Class
Route
ORAL
Patents
0
Programs
2
Data quality
0.84

Quick answer

tazemetostat hydrobromide (TAZVERIK) is a histone-lysine n-methyltransferase ezh2 inhibitor. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN tazemetostat hydrobromide
Brand TAZVERIK
Mechanism Histone-lysine N-methyltransferase EZH2 inhibitor
Target Histone-lysine N-methyltransferase EZH2
Route ORAL
Formulation TABLET

Mechanism of action

Histone-lysine N-methyltransferase EZH2 inhibitor

Primary target: Histone-lysine N-methyltransferase EZH2

Approval history

Authority Status Date
FDA approved
PMDA approved

Pipeline programs

  1. IB 2019-04 Phase 2 · George Institute for · Adult participants with metastatic or unresectable locally a
  2. Tazemetostat Phase 2 · Eisai · Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma

Frequently asked questions

What is tazemetostat hydrobromide?

tazemetostat hydrobromide (TAZVERIK) is a histone-lysine n-methyltransferase ezh2 inhibitor. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for tazemetostat hydrobromide?

TAZVERIK is a marketed brand name for tazemetostat hydrobromide. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of tazemetostat hydrobromide?

tazemetostat hydrobromide has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.