Wednesday, July 8, 2026

Drug profile · INN

sumatriptan

sumatriptan (APO-SUMATRIPTAN) is a serotonin 1b (5-ht1b) receptor agonist. Associated with Alphapharm Pty Ltd. Route of administration: oral. Current US regulatory status: approved.

FDA: approved EMA: refused TGA: approved
US status approved
Patents linked 2
Pipeline programs 4
News articles 0
Drug details — sumatriptan
US status
approved
Class
Route
ORAL
Patents
2
Programs
4
Data quality
0.89

Quick answer

sumatriptan (APO-SUMATRIPTAN) is a serotonin 1b (5-ht1b) receptor agonist. Associated with Alphapharm Pty Ltd. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN sumatriptan
Brand APO-SUMATRIPTAN
Mechanism Serotonin 1b (5-HT1b) receptor agonist
Target 5-hydroxytryptamine receptor 1B
Route ORAL
Formulation SPRAY

Mechanism of action

Serotonin 1b (5-HT1b) receptor agonist

Primary target: 5-hydroxytryptamine receptor 1B

Approval history

Authority Status Date
FDA approved
EMA refused
TGA approved

Pipeline programs

  1. NP101 Sumatriptan Iontophoretic Transdermal Patch Phase 3 · Teva Pharma · Migraine Disorders
  2. Sumatriptan succinate Phase 1 · Teva Pharma · Healthy
  3. Sumatriptan succinate Phase 1 · Teva Pharma · Migraine Disorders
  4. MAMBO-II Approved · George Institute for · Migraine

Related & competitor drugs

  1. almotriptan malate Serotonin 1f (5-HT1f) receptor agonist
  2. eletriptan hydrobromide Serotonin 1b (5-HT1b) receptor agonist
  3. frovatriptan succinate Serotonin 1b (5-HT1b) receptor agonist
  4. rizatriptan benzoate Serotonin 1d (5-HT1d) receptor agonist
  5. sumatriptan succinate Serotonin 1d (5-HT1d) receptor agonist
  6. zolmitriptan Serotonin 1d (5-HT1d) receptor agonist
  1. US 12090139

    Formulations comprising triptan compounds

    Expires Mon Sep 12 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 9427578

    Pharmacokinetics of iontophoretic sumatriptan administration

    Expires Mon Aug 25 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is sumatriptan?

sumatriptan (APO-SUMATRIPTAN) is a serotonin 1b (5-ht1b) receptor agonist. Associated with Alphapharm Pty Ltd. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for sumatriptan?

APO-SUMATRIPTAN is a marketed brand name for sumatriptan. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of sumatriptan?

sumatriptan has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.