Friday, July 10, 2026

Drug profile · INN

spesolimab

spesolimab (SPEVIGO) is a il36 receptor antagonist.

EMA: approved Antineoplastic and immunomodulating agents (L04) L04AC22
Patents linked 0
Pipeline programs 9
News articles 0
Drug details — spesolimab
Class
Antineoplastic and immunomodulating agents (L04)
Route
Patents
0
Programs
9
Data quality
0.83

Quick answer

spesolimab (SPEVIGO) is a il36 receptor antagonist.

Key facts

INN spesolimab
Brand SPEVIGO
Mechanism IL36 receptor antagonist
Target IL36 receptor
Therapeutic class Antineoplastic and immunomodulating agents (L04)
ATC code L04AC22

Mechanism of action

IL36 receptor antagonist

Primary target: IL36 receptor

Approval history

Authority Status Date
EMA approved

Pipeline programs

  1. Placebo matching to spesolimab Phase 3 · Boehringer Ingelheim · Pyoderma gangrenosum
  2. Spesolimab - solution for infusion Phase 3 · Boehringer Ingelheim · Netherton Syndrome
  3. Spesolimab i.v. Phase 3 · Boehringer Ingelheim · Hidradenitis Suppurativa
  4. Spesolimab, Placebo matching to Spesolimab Phase 3 · Boehringer Ingelheim · Hidradenitis Suppurativa (HS)
  5. Spesolimab Phase 2 · Boehringer Ingelheim · Generalized Pustular Psoriasis
  6. 1368-0151 Phase 1 · Boehringer Ingelheim · Healthy volunteer trial
  7. PDY18058 Phase 1 · Sanofi-Aventis U.S · Immuun system diseases
  8. Spesolimab Phase 1 · Boehringer Ingelheim · Psoriasis

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. axitinib Antineoplastic and immunomodulating agents (L01)
  6. azacitidine Antineoplastic and immunomodulating agents (L01)

Frequently asked questions

What is spesolimab?

spesolimab (SPEVIGO) is a il36 receptor antagonist.

What is the brand name for spesolimab?

SPEVIGO is a marketed brand name for spesolimab. Check FDA Drugs@FDA for the current US label holder and prescribing information.