Wednesday, July 8, 2026

Drug profile · INN

sorafenib tosylate

sorafenib tosylate (NEXAVAR) is a vascular endothelial growth factor receptor inhibitor. Associated with Teva Pharma GmbH. Route of administration: oral. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 0
Pipeline programs 9
News articles 0
Drug details — sorafenib tosylate
US status
approved
Class
Route
ORAL
Patents
0
Programs
9
Data quality
0.89

Quick answer

sorafenib tosylate (NEXAVAR) is a vascular endothelial growth factor receptor inhibitor. Associated with Teva Pharma GmbH. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN sorafenib tosylate
Brand NEXAVAR
Mechanism Vascular endothelial growth factor receptor inhibitor
Target Platelet-derived growth factor receptor beta
Route ORAL
Formulation TABLET

Mechanism of action

Vascular endothelial growth factor receptor inhibitor

Primary target: Platelet-derived growth factor receptor beta

Approval history

Authority Status Date
FDA approved

Pipeline programs

  1. D419CC00002 Phase 3 · AstraZeneca · Advanced hepatocellular carcinoma (HCC)
  2. Sorafenib Phase 3 · Chinese Academy of · Hepatocellular Carcinoma
  3. Sorafenib Phase 3 · First People's Hospital · Acute Myeloid Leukemia
  4. Sorafenib (Nexavar, BAY43-9006) Phase 3 · Bayer HealthCare Animal · Carcinoma
  5. Sorafenib (Nexavar, BAY43-9006) Phase 3 · Bayer HealthCare Animal · Carcinoma, Hepatocellular
  6. Sorafenib Phase 2 · United Therapeutics Europe · Lung Cancer
  7. Sorafenib (Nexavar, BAY43-9006) plus Doxorubicin Phase 2 · Bayer HealthCare Animal · Carcinoma, Hepatocellular
  8. DPH001-01 Phase 1 · Anaxis Pharma · Hepatocellular carcinoma, renal cell carcinoma and different

Related & competitor drugs

  1. tivozanib hydrochloride Vascular endothelial growth factor receptor inhibitor
  2. tivozanib hydrochloride monohydrate Antineoplastic and immunomodulating agents (L01)
  3. anlotinib Platelet-derived growth factor receptor beta inhibitor

Frequently asked questions

What is sorafenib tosylate?

sorafenib tosylate (NEXAVAR) is a vascular endothelial growth factor receptor inhibitor. Associated with Teva Pharma GmbH. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for sorafenib tosylate?

NEXAVAR is a marketed brand name for sorafenib tosylate. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of sorafenib tosylate?

sorafenib tosylate has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.