Friday, July 10, 2026

Drug profile · INN

sorafenib

sorafenib (NEXAVAR) is a vascular endothelial growth factor receptor inhibitor. Associated with Bayer Australia Ltd.

EMA: approved TGA: approved NMPA: clinical trials Antineoplastic and immunomodulating agents (L01) L01EX02
Patents linked 3
Pipeline programs 12
News articles 0
Drug details — sorafenib
Class
Antineoplastic and immunomodulating agents (L01)
Route
Patents
3
Programs
12
Data quality
0.83

Quick answer

sorafenib (NEXAVAR) is a vascular endothelial growth factor receptor inhibitor. Associated with Bayer Australia Ltd.

Key facts

INN sorafenib
Brand NEXAVAR
Mechanism Vascular endothelial growth factor receptor inhibitor
Therapeutic class Antineoplastic and immunomodulating agents (L01)
ATC code L01EX02

Mechanism of action

Vascular endothelial growth factor receptor inhibitor

Approval history

Authority Status Date
EMA approved
TGA approved
NMPA clinical trials

Pipeline programs

  1. CA209-9DW Phase 3 · Bristol-Myers Squibb Australia · Hepatocellular Carcinoma, Hepatocellular Carcinoma, Hepatoce
  2. Experimental: Venetoclax in combination with Decitabine (+-sorafenib) Phase 3 · Kunming Hope of · Elderly AML Patients
  3. Sorafenib Phase 3 · Chinese Academy of · Hepatocellular Carcinoma
  4. Sorafenib Phase 3 · First People's Hospital · Acute Myeloid Leukemia
  5. Sorafenib (Nexavar, BAY43-9006) Phase 3 · Bayer HealthCare Animal · Carcinoma, Hepatocellular
  6. Sorafenib (Nexavar, BAY43-9006) Phase 3 · Bayer HealthCare Animal · Carcinoma
  7. M24-147 Phase 2 · AbbVie Deutschland GmbH · Hepatocellular Carcinoma
  8. Sorafenib Phase 2 · United Therapeutics Europe · Lung Cancer

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. axitinib Antineoplastic and immunomodulating agents (L01)
  6. azacitidine Antineoplastic and immunomodulating agents (L01)
  1. US 10933076

    Crocin-sorafenib combination therapy for liver cancer

    Expires Mon Feb 25 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 10568873

    Safranal-sorafenib combination therapy for liver cancer

    Expires Mon Feb 20 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10449182

    Sorafenib derivatives as p21 inhibitors

    Expires Mon Oct 17 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is sorafenib?

sorafenib (NEXAVAR) is a vascular endothelial growth factor receptor inhibitor. Associated with Bayer Australia Ltd.

What is the brand name for sorafenib?

NEXAVAR is a marketed brand name for sorafenib. Check FDA Drugs@FDA for the current US label holder and prescribing information.