Wednesday, July 8, 2026

Drug profile · INN

sarilumab

sarilumab (KEVZARA) is a interleukin-6 receptor alpha subunit antagonist. Route of administration: injection. Current US regulatory status: approved.

FDA: approved EMA: approved PMDA: approved Antineoplastic and immunomodulating agents (L04) L04AC14
US status approved
Patents linked 0
Pipeline programs 16
News articles 0
Drug details — sarilumab
US status
approved
Class
Antineoplastic and immunomodulating agents (L04)
Route
INJECTION
Patents
0
Programs
16
Data quality
0.84

Quick answer

sarilumab (KEVZARA) is a interleukin-6 receptor alpha subunit antagonist. Route of administration: injection. Current US regulatory status: approved.

Key facts

INN sarilumab
Brand KEVZARA
Mechanism Interleukin-6 receptor alpha subunit antagonist
Target Interleukin-6 receptor subunit alpha
Therapeutic class Antineoplastic and immunomodulating agents (L04)
Route INJECTION
Formulation INJECTABLE
ATC code L04AC14

Mechanism of action

Interleukin-6 receptor alpha subunit antagonist

Primary target: Interleukin-6 receptor subunit alpha

Approval history

Authority Status Date
FDA approved
EMA approved
PMDA approved

Pipeline programs

  1. Sarilumab Phase 3 · Sanofi Pasteur MSD · Rheumatoid Arthritis
  2. Sarilumab Phase 3 · Regeneron UK · COVID-19
  3. Sarilumab Phase 3 · Regeneron UK · RA
  4. Sarilumab SAR153191 Phase 3 · Regeneron UK · Giant Cell Arteritis
  5. Sarilumab SAR153191 Phase 3 · Regeneron UK · Corona Virus Infection
  6. Sarilumab SAR153191 (REGN88) Phase 3 · Regeneron UK · Polymyalgia Rheumatica
  7. sarilumab SAR153191 (REGN88) Phase 3 · Regeneron UK · Rheumatoid Arthritis
  8. R4018-ONC-1721 Phase 2 · Anaxis Pharma · Fallopian Tube Cancer, Endometrial Cancer, Ovarian Cancer, P

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. axitinib Antineoplastic and immunomodulating agents (L01)
  6. azacitidine Antineoplastic and immunomodulating agents (L01)

Frequently asked questions

What is sarilumab?

sarilumab (KEVZARA) is a interleukin-6 receptor alpha subunit antagonist. Route of administration: injection. Current US regulatory status: approved.

What is the brand name for sarilumab?

KEVZARA is a marketed brand name for sarilumab. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of sarilumab?

sarilumab has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.