Drug profile · INN
sacituzumab govitecan
TRODELVY
sacituzumab govitecan (TRODELVY) is a dna topoisomerase i inhibitor. Associated with Gilead Sciences Pty Limited.
Drug details — sacituzumab govitecan
- Class
- Antineoplastic and immunomodulating agents (L01)
- Route
- —
- Patents
- 0
- Programs
- 14
- Data quality
- 0.83
Quick answer
sacituzumab govitecan (TRODELVY) is a dna topoisomerase i inhibitor. Associated with Gilead Sciences Pty Limited.
Key facts
Mechanism of action
DNA topoisomerase I inhibitor
Primary target: DNA topoisomerase 1
Approval history
| Authority | Status | Date |
|---|---|---|
| EMA | approved | — |
| TGA | approved | — |
Recent coverage
Merck and Gilead report mixed outcomes in lung cancer and HIV studies
Merck Gilead report mixed outcomes in key lung cancer and HIV studies: a Phase 3 Trodelvy plus KEYTRUDA lung cancer trial was halted, while two Phase 3 HIV studies for islatravir/lenacapavir reported positive topline results. This plan focuses on the business and clinical implications for analysts and BD teams.
Datroway and Trodelvy Vie for First-Line TNBC Dominance Amidst Evolving Treatment Landscape
Datroway and Trodelvy, two TROP2-targeting antibody-drug conjugates, are poised to enter a head-to-head competition in the first-line treatment of triple-negative breast cancer (TNBC). This evolving landscape presents significant strategic considerations for pharmaceutical business development and investment.
Antibody-Drug Conjugates in Breast Cancer: Enhertu vs. Trodelvy in EU Market
This article compares Enhertu and Trodelvy, two leading antibody-drug conjugates, in their effectiveness for breast cancer treatment in the EU market.
Pipeline programs
Related & competitor drugs
Frequently asked questions
What is sacituzumab govitecan?
sacituzumab govitecan (TRODELVY) is a dna topoisomerase i inhibitor. Associated with Gilead Sciences Pty Limited.
What is the brand name for sacituzumab govitecan?
TRODELVY is a marketed brand name for sacituzumab govitecan. Check FDA Drugs@FDA for the current US label holder and prescribing information.