Saturday, July 11, 2026

Drug profile · INN

roxadustat

roxadustat (EVRENZO) is a hypoxia-inducible factor prolyl hydroxylase inhibitor.

EMA: approved PMDA: approved NMPA: clinical trials Blood and blood forming organs (B03) B03XA05
Patents linked 0
Pipeline programs 2
News articles 0
Drug details — roxadustat
Class
Blood and blood forming organs (B03)
Route
Patents
0
Programs
2
Data quality
0.83

Quick answer

roxadustat (EVRENZO) is a hypoxia-inducible factor prolyl hydroxylase inhibitor.

Key facts

INN roxadustat
Brand EVRENZO
Mechanism Hypoxia-inducible factor prolyl hydroxylase inhibitor
Target Hypoxia-inducible factor prolyl hydroxylase
Therapeutic class Blood and blood forming organs (B03)
ATC code B03XA05

Mechanism of action

Hypoxia-inducible factor prolyl hydroxylase inhibitor

Primary target: Hypoxia-inducible factor prolyl hydroxylase

Approval history

Authority Status Date
EMA approved
PMDA approved
NMPA clinical trials

Pipeline programs

  1. Roxadustat Phase 3 · AstraZeneca · Anemia
  2. Roxadustat Phase 2 · Peking University Biologics · Coronary Artery Bypass

Related & competitor drugs

  1. apixaban Blood and blood forming organs (B01)
  2. berotralstat Blood and blood forming organs (B06)
  3. bivalirudin Blood and blood forming organs (B01)
  4. c1 inhibitor (human) Blood and blood forming organs (B06)
  5. clopidogrel Blood and blood forming organs (B01)
  6. dabigatran etexilate Blood and blood forming organs (B01)

Frequently asked questions

What is roxadustat?

roxadustat (EVRENZO) is a hypoxia-inducible factor prolyl hydroxylase inhibitor.

What is the brand name for roxadustat?

EVRENZO is a marketed brand name for roxadustat. Check FDA Drugs@FDA for the current US label holder and prescribing information.