Friday, July 10, 2026

Drug profile · INN

ravulizumab

ravulizumab (ULTOMIRIS) is a complement c5 inhibitor. Associated with Lacuna Pharma Pty Ltd.

EMA: approved TGA: approved Antineoplastic and immunomodulating agents (L04) L04AA43
Patents linked 0
Pipeline programs 13
News articles 0
Drug details — ravulizumab
Class
Antineoplastic and immunomodulating agents (L04)
Route
Patents
0
Programs
13
Data quality
0.83

Quick answer

ravulizumab (ULTOMIRIS) is a complement c5 inhibitor. Associated with Lacuna Pharma Pty Ltd.

Key facts

INN ravulizumab
Brand ULTOMIRIS
Mechanism Complement C5 inhibitor
Target Complement C5
Therapeutic class Antineoplastic and immunomodulating agents (L04)
ATC code L04AA43

Mechanism of action

Complement C5 inhibitor

Primary target: Complement C5

Approval history

Authority Status Date
EMA approved
TGA approved

Pipeline programs

  1. ALXN1210-DGF-321 Phase 3 · Alexion Europe SAS · Delayed Graft Function after Kidney Transplantation
  2. ALXN1210-IgAN-320 Phase 3 · Alexion Europe SAS · Immunoglobulin A Nephropathy (IgAN)
  3. ALXN1210-IgAN-325 Phase 3 · Alexion Europe SAS · Immunoglobulin A Nephropathy
  4. ALXN1210-TMA-313 Phase 3 · Alexion Europe SAS · Hematopoietic stem cell transplant-associated thrombotic mic
  5. ALXN2040-PNH-303 Phase 3 · Alexion Europe SAS · Patients with Paroxysmal Nocturnal Hemoglobinuria
  6. R3918-PNH-2021 Phase 3 · Anaxis Pharma · Paroxysmal nocturnal haemoglobinuria (PNH)
  7. Ravulizumab Phase 3 · Regeneron UK · Paroxysmal Nocturnal Hemoglobinuria
  8. Ravulizumab Phase 3 · Alexion Europe SAS · Atypical Hemolytic Uremic Syndrome (aHUS)

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. axitinib Antineoplastic and immunomodulating agents (L01)
  6. azacitidine Antineoplastic and immunomodulating agents (L01)

Frequently asked questions

What is ravulizumab?

ravulizumab (ULTOMIRIS) is a complement c5 inhibitor. Associated with Lacuna Pharma Pty Ltd.

What is the brand name for ravulizumab?

ULTOMIRIS is a marketed brand name for ravulizumab. Check FDA Drugs@FDA for the current US label holder and prescribing information.