Friday, July 10, 2026

Drug profile · INN

pyrotinib

pyrotinib is a receptor protein-tyrosine kinase erbb-2 inhibitor.

NMPA: clinical trials
Patents linked 0
Pipeline programs 6
News articles 0
Drug details — pyrotinib
Class
Route
Patents
0
Programs
6
Data quality
0.70

Quick answer

pyrotinib is a receptor protein-tyrosine kinase erbb-2 inhibitor.

Key facts

INN pyrotinib
Mechanism Receptor protein-tyrosine kinase erbB-2 inhibitor
Target Epidermal growth factor receptor

Mechanism of action

Receptor protein-tyrosine kinase erbB-2 inhibitor

Primary target: Epidermal growth factor receptor

Approval history

Authority Status Date
NMPA clinical trials

Pipeline programs

  1. Fulvestrant combined with Pyrotinib Phase 3 · Sun Yat-sen Memorial · Breast Cancer
  2. NJMU-BC01 Phase 2 · First People's Hospital · Breast Cancer
  3. Neoadjuvant therapy: TCbHPy Phase 2 · First People's Hospital · Breast Cancer
  4. Pyrotinib Phase 2 · First People's Hospital · Breast Cancer
  5. pyrotinib and trastuzumab in combinition with neoadjuvant chemotherapy Phase 2 · First People's Hospital · HER2-positive Breast Cancer
  6. Pyrotinib low dose group Phase 1 · Chinese Academy of · Breast Cancer

Related & competitor drugs

  1. erlotinib hydrochloride Epidermal growth factor receptor erbB1 inhibitor
  2. lapatinib ditosylate Receptor protein-tyrosine kinase erbB-2 inhibitor
  3. mobocertinib Antineoplastic and immunomodulating agents (L01)
  4. mobocertinib succinate Epidermal growth factor receptor erbB1 inhibitor
  5. neratinib maleate Receptor protein-tyrosine kinase erbB-2 inhibitor
  6. afatinib dimaleate Epidermal growth factor receptor erbB1 inhibitor

Frequently asked questions

What is pyrotinib?

pyrotinib is a receptor protein-tyrosine kinase erbb-2 inhibitor.