Wednesday, July 8, 2026

Drug profile · INN

propoxyphene napsylate

propoxyphene napsylate (DARVON-N) is a mu opioid receptor agonist. Associated with Dyne Therapeutics. Route of administration: oral. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 15
Pipeline programs 0
News articles 0
Drug details — propoxyphene napsylate
US status
approved
Class
Route
ORAL
Patents
15
Programs
0
Data quality
0.89

Quick answer

propoxyphene napsylate (DARVON-N) is a mu opioid receptor agonist. Associated with Dyne Therapeutics. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN propoxyphene napsylate
Brand DARVON-N
Mechanism Mu opioid receptor agonist
Target Mu-type opioid receptor
Route ORAL
Formulation TABLET

Mechanism of action

Mu opioid receptor agonist

Primary target: Mu-type opioid receptor

Approval history

Authority Status Date
FDA approved

Related & competitor drugs

  1. alvimopan Mu opioid receptor antagonist
  2. loperamide hydrochloride Mu opioid receptor agonist
  3. methadone hydrochloride Mu opioid receptor agonist
  4. morphine sulfate Mu opioid receptor agonist
  5. oxycodone Mu opioid receptor agonist
  6. oxycodone hydrochloride Mu opioid receptor agonist
  1. US 12168648

    Opioid receptor modulators

    Expires Mon Dec 12 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11723762

    LIDAR based 3-D imaging with far-field illumination overlap

    Expires Mon Aug 10 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11634396

    Opioid receptor modulators

    Expires Mon Apr 20 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11634452

    Compounds for treating neurodegenerative disorders

    Expires Mon Apr 20 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 11129864

    Method for obtaining a plant extract and associated compositions

    Expires Mon Sep 23 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10933086

    Composition for preventing, alleviating, or treating arthritis or osteoporosis, containing neoagarooligosaccharide

    Expires Mon Feb 25 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 9999647

    Method for obtaining a plant extract and associated compositions

    Expires Mon Jun 14 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 9279366

    Steam powered engine

    Expires Mon Mar 03 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 7811297

    Actuable structures and methods of fabrication and use

    Expires Mon Oct 07 2030 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 7777027

    Purified beta glucan composition

    Expires Mon Aug 12 2030 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 7550584

    Methods of purifying beta glucans

    Expires Mon Jun 18 2029 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 7361476

    Methionyl tRNA synthetase polynucleotides

    Expires Mon Apr 17 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 7335499

    tRNA synthetase

    Expires Mon Feb 21 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 6989255

    Methionyl tRNA synthetase polypeptides from Staphylococcus aureus

    Expires Mon Jan 19 2026 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired
  15. US 6162787

    Methods for treating arthritis using collagen type II, glucosamine chondroitin sulfate, and compositions

    Expires Mon Dec 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired

Frequently asked questions

What is propoxyphene napsylate?

propoxyphene napsylate (DARVON-N) is a mu opioid receptor agonist. Associated with Dyne Therapeutics. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for propoxyphene napsylate?

DARVON-N is a marketed brand name for propoxyphene napsylate. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of propoxyphene napsylate?

propoxyphene napsylate has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.