Wednesday, July 8, 2026

Drug profile · INN

propofol

propofol (DIPRIVAN) is a gaba-a receptor; anion channel positive allosteric modulator. Associated with Amneal Pharma Europe Ltd. Route of administration: injection. Current US regulatory status: approved.

FDA: approved NMPA: clinical trials
US status approved
Patents linked 3
Pipeline programs 16
News articles 0
Drug details — propofol
US status
approved
Class
Route
INJECTION
Patents
3
Programs
16
Data quality
0.89

Quick answer

propofol (DIPRIVAN) is a gaba-a receptor; anion channel positive allosteric modulator. Associated with Amneal Pharma Europe Ltd. Route of administration: injection. Current US regulatory status: approved.

Key facts

INN propofol
Brand DIPRIVAN
Mechanism GABA-A receptor; anion channel positive allosteric modulator
Target GABA-A receptor; anion channel
Route INJECTION
Formulation INJECTABLE

Mechanism of action

GABA-A receptor; anion channel positive allosteric modulator

Primary target: GABA-A receptor; anion channel

Approval history

Authority Status Date
FDA approved
NMPA clinical trials

Pipeline programs

  1. APHP230844 Phase 3 · PARItec · Adult patients with severe cardiogenic shock on venoarterial
  2. HSK3486-309 Phase 3 · Anaxis Pharma · General anaesthesia
  3. IIBSP-SAV-2025-178 Phase 3 · George Institute for · Acute ischemic stroke
  4. Fospropofol disodium Phase 1 · Chinese Academy of · Drug Safety
  5. Fospropofol disodium Phase 1 · Hospital Authority · Drug Safety
  6. Group C : Saline + propofol group Approved · Hospital Authority · Urologic Surgery
  7. Propofol Approved · Chinese Academy of · Urinary Surgery
  8. Propofol Approved · Chinese Academy of · Nausea and Vomiting

Related & competitor drugs

  1. acamprosate calcium GABA-A receptor; anion channel positive modulator
  2. alprazolam GABA-A receptor; anion channel positive allosteric modulator
  3. butabarbital sodium GABA-A receptor; anion channel positive allosteric modulator
  4. chlordiazepoxide hydrochloride GABA-A receptor; anion channel positive allosteric modulator
  5. clobazam GABA-A receptor; anion channel positive allosteric modulator
  6. clonazepam GABA-A receptor; anion channel positive allosteric modulator
  1. US 11357743

    Ketamine and propofol admixture

    Expires Mon Jun 09 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 7468394

    Sterile pharmaceutical composition and process for a solution of propofol emulsion having microbial growth retardation

    Expires Mon Dec 18 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 6399087

    Propofol formulation with enhanced microbial inhibition

    Expires Mon May 30 2022 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired

Frequently asked questions

What is propofol?

propofol (DIPRIVAN) is a gaba-a receptor; anion channel positive allosteric modulator. Associated with Amneal Pharma Europe Ltd. Route of administration: injection. Current US regulatory status: approved.

What is the brand name for propofol?

DIPRIVAN is a marketed brand name for propofol. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of propofol?

propofol has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.