Saturday, July 11, 2026

Drug profile · INN

polatuzumab vedotin

polatuzumab vedotin (POLIVY) is a b-cell antigen receptor complex-associated protein beta chain binding agent.

EMA: approved Antineoplastic and immunomodulating agents (L01) L01FX14
Patents linked 0
Pipeline programs 9
News articles 0
Drug details — polatuzumab vedotin
Class
Antineoplastic and immunomodulating agents (L01)
Route
Patents
0
Programs
9
Data quality
0.83

Quick answer

polatuzumab vedotin (POLIVY) is a b-cell antigen receptor complex-associated protein beta chain binding agent.

Key facts

INN polatuzumab vedotin
Brand POLIVY
Mechanism B-cell antigen receptor complex-associated protein beta chain binding agent
Target B-cell antigen receptor complex-associated protein beta chain
Therapeutic class Antineoplastic and immunomodulating agents (L01)
ATC code L01FX14

Mechanism of action

B-cell antigen receptor complex-associated protein beta chain binding agent

Primary target: B-cell antigen receptor complex-associated protein beta chain

Approval history

Authority Status Date
EMA approved

Pipeline programs

  1. GO39942 Phase 3 · HOFFMANN-LA ROCHE · Previously Untreated Diffuse large B-cell lymphoma (DLBCL)
  2. MO40598 Phase 3 · HOFFMANN-LA ROCHE · Relapsed/refractory diffuse large B-cell lymphoma (DLBCL)
  3. GO40516 Phase 2 · HOFFMANN-LA ROCHE · B-cell non-Hodgkin lymphoma (NHL)
  4. GO40554 Phase 2 · HOFFMANN-LA ROCHE · Diffuse Large B-Cell Lymphoma (DLBCL)
  5. Glofitamab for previously untreated aggressive B-cell lymphoma Phase 2 · George Institute for · previously untreated aggressive B-cell lymphoma
  6. M22-132 Phase 2 · AbbVie Deutschland GmbH · B-cell Non-Hodgkin's lymphoma, diffuse large B-cell lymphoma
  7. MK-2140-011 Phase 2 · MSD Merck Sharp · Diffuse Large B-Cell Lymphoma (DLBCL)
  8. NP39488 Phase 2 · HOFFMANN-LA ROCHE · Relapsed/refractory (r/r) B-cell Non-Hodgkin’s Lymphoma (NHL

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. axitinib Antineoplastic and immunomodulating agents (L01)
  6. azacitidine Antineoplastic and immunomodulating agents (L01)

Frequently asked questions

What is polatuzumab vedotin?

polatuzumab vedotin (POLIVY) is a b-cell antigen receptor complex-associated protein beta chain binding agent.

What is the brand name for polatuzumab vedotin?

POLIVY is a marketed brand name for polatuzumab vedotin. Check FDA Drugs@FDA for the current US label holder and prescribing information.