Wednesday, July 8, 2026

Drug profile · INN

permethrin

permethrin (LYCLEAR) is a voltage-sensitive sodium channel blocker. Route of administration: topical. Current US regulatory status: approved.

FDA: approved TGA: approved
US status approved
Patents linked 3
Pipeline programs 3
News articles 0
Drug details — permethrin
US status
approved
Class
Route
TOPICAL
Patents
3
Programs
3
Data quality
0.84

Quick answer

permethrin (LYCLEAR) is a voltage-sensitive sodium channel blocker. Route of administration: topical. Current US regulatory status: approved.

Key facts

INN permethrin
Brand LYCLEAR
Mechanism Voltage-sensitive sodium channel blocker
Target Voltage-sensitive sodium channel
Route TOPICAL
Formulation LOTION

Mechanism of action

Voltage-sensitive sodium channel blocker

Primary target: Voltage-sensitive sodium channel

Approval history

Authority Status Date
FDA approved
TGA approved

Pipeline programs

  1. ETSKABI Phase 3 · Alphapharm · Scabies
  2. Permethrin, InfectoScab® 5 % Crème Phase 3 · Alphapharm · Scabies
  3. Permethrin Foam 4% Phase 2 · VYNE Therapeutics · Scabies

Related patents

  1. US 11219631

    Foamable compositions, breakable foams and their uses

    Expires Mon Jan 06 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11103454

    Wax foamable vehicle and pharmaceutical compositions thereof

    Expires Mon Aug 26 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11033491

    Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof

    Expires Mon Jun 10 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is permethrin?

permethrin (LYCLEAR) is a voltage-sensitive sodium channel blocker. Route of administration: topical. Current US regulatory status: approved.

What is the brand name for permethrin?

LYCLEAR is a marketed brand name for permethrin. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of permethrin?

permethrin has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.