Wednesday, July 8, 2026

Drug profile · INN

pentoxifylline

pentoxifylline (PENTOXIFYLLINE) is a 3',5'-cyclic phosphodiesterase inhibitor. Route of administration: oral. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 0
Pipeline programs 2
News articles 0
Drug details — pentoxifylline
US status
approved
Class
Route
ORAL
Patents
0
Programs
2
Data quality
0.84

Quick answer

pentoxifylline (PENTOXIFYLLINE) is a 3',5'-cyclic phosphodiesterase inhibitor. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN pentoxifylline
Brand PENTOXIFYLLINE
Mechanism 3',5'-cyclic phosphodiesterase inhibitor
Target 3',5'-cyclic phosphodiesterase
Route ORAL
Formulation TABLET, EXTENDED RELEASE

Mechanism of action

3',5'-cyclic phosphodiesterase inhibitor

Primary target: 3',5'-cyclic phosphodiesterase

Approval history

Authority Status Date
FDA approved

Pipeline programs

  1. Pentoxifylline Phase 3 · United Therapeutics Europe · Kidney Failure, Chronic
  2. 15/0483 Phase 1 · United Therapeutics Europe · Head and Neck Fibrosis

Related & competitor drugs

  1. cilostazol Phosphodiesterase 3A inhibitor
  2. dyphylline Phosphodiesterase 4 inhibitor
  3. sildenafil citrate Phosphodiesterase 5A inhibitor
  4. tadalafil Genito-urinary system and sex hormones (G04)
  5. vardenafil hydrochloride Phosphodiesterase 5A inhibitor
  6. avanafil Genito-urinary system and sex hormones (G04)

Frequently asked questions

What is pentoxifylline?

pentoxifylline (PENTOXIFYLLINE) is a 3',5'-cyclic phosphodiesterase inhibitor. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for pentoxifylline?

PENTOXIFYLLINE is a marketed brand name for pentoxifylline. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of pentoxifylline?

pentoxifylline has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.