Wednesday, July 8, 2026

Drug profile · INN

oxymetazoline

oxymetazoline (DRIXINE) is a adrenergic receptor alpha agonist. Associated with Lacuna Pharma Pty Ltd. Route of administration: topical. Current US regulatory status: approved.

FDA: approved TGA: approved
US status approved
Patents linked 1
Pipeline programs 8
News articles 0
Drug details — oxymetazoline
US status
approved
Class
Route
TOPICAL
Patents
1
Programs
8
Data quality
0.89

Quick answer

oxymetazoline (DRIXINE) is a adrenergic receptor alpha agonist. Associated with Lacuna Pharma Pty Ltd. Route of administration: topical. Current US regulatory status: approved.

Key facts

INN oxymetazoline
Brand DRIXINE
Mechanism Adrenergic receptor alpha agonist
Route TOPICAL
Formulation CREAM

Mechanism of action

Adrenergic receptor alpha agonist

Approval history

Authority Status Date
FDA approved
TGA approved

Pipeline programs

  1. 101380003SA Phase 3 · Santen Oy · Acquired Blepharoptosis
  2. Oxymetazoline Hydrochloride Phase 3 · Teva Pharma · Rosacea
  3. Nasal Carbon Dioxide Phase 2 · United Therapeutics Europe · Migraine
  4. Oxymetazoline Phase 1 · United Therapeutics Europe · Fecal Incontinence
  5. Oxymetazoline HCL 1.0% Cream Approved · Aclaris Therapeutics · Rosacea
  6. Rapid Acting insulin with pre-treatment of rHuPH20 Approved · HALOZYME THERAPEUTICS · Type 1 Diabetes Mellitus
  7. 20250527IIT0060 Unknown · Chinese Academy of · Dexmedetomidine Induced Sedation
  8. Rapid test for diagnosis orientation Unknown · Grace Therapeutics · Flu
  1. US 10335391

    Stabilized oxymetazoline formulations and their uses

    Expires Mon Jun 27 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is oxymetazoline?

oxymetazoline (DRIXINE) is a adrenergic receptor alpha agonist. Associated with Lacuna Pharma Pty Ltd. Route of administration: topical. Current US regulatory status: approved.

What is the brand name for oxymetazoline?

DRIXINE is a marketed brand name for oxymetazoline. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of oxymetazoline?

oxymetazoline has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.