Friday, July 10, 2026

Drug profile · INN

osimertinib mesilate

osimertinib mesilate (TAGRISSO) is a epidermal growth factor receptor erbb1 inhibitor.

PMDA: approved
Patents linked 0
Pipeline programs 21
News articles 0
Drug details — osimertinib mesilate
Class
Route
Patents
0
Programs
21
Data quality
0.78

Quick answer

osimertinib mesilate (TAGRISSO) is a epidermal growth factor receptor erbb1 inhibitor.

Key facts

INN osimertinib mesilate
Brand TAGRISSO
Mechanism Epidermal growth factor receptor erbB1 inhibitor
Target Epidermal growth factor receptor

Mechanism of action

Epidermal growth factor receptor erbB1 inhibitor

Primary target: Epidermal growth factor receptor

Approval history

Authority Status Date
PMDA approved

Pipeline programs

  1. 73841937NSC3003 Phase 3 · Janssen-Cilag International N.V · EGFR-mutated locally advanced or metastatic Non Small Cell L
  2. ADAURA - D5164C00001 Phase 3 · AstraZeneca · Stage IB-IIIA non-small cell lung carcinoma, with a centrall
  3. D5087C00001 Phase 3 · AstraZeneca · Non-Small Cell Lung Cancer
  4. D5160C00048 Phase 3 · AstraZeneca · Histologically documented non-small cell lung cancer of pred
  5. D5162C00042 Phase 3 · AstraZeneca · Non-Small Cell Lung Cancer
  6. D5169C00001 FLAURA2 Phase 3 · AstraZeneca · Patients with locally-advanced or metastatic EGFRm (Ex19del
  7. D516AC00001 Phase 3 · AstraZeneca · Patients with histologically or cytologically documented non
  8. D516FC00001(ADAURA2) Phase 3 · AstraZeneca · Stage IA2-IA3 non-small cell lung carcinoma, with EGFR mutat

Related & competitor drugs

  1. erlotinib hydrochloride Epidermal growth factor receptor erbB1 inhibitor
  2. lapatinib ditosylate Receptor protein-tyrosine kinase erbB-2 inhibitor
  3. mobocertinib Antineoplastic and immunomodulating agents (L01)
  4. mobocertinib succinate Epidermal growth factor receptor erbB1 inhibitor
  5. neratinib maleate Receptor protein-tyrosine kinase erbB-2 inhibitor
  6. afatinib dimaleate Epidermal growth factor receptor erbB1 inhibitor

Frequently asked questions

What is osimertinib mesilate?

osimertinib mesilate (TAGRISSO) is a epidermal growth factor receptor erbb1 inhibitor.

What is the brand name for osimertinib mesilate?

TAGRISSO is a marketed brand name for osimertinib mesilate. Check FDA Drugs@FDA for the current US label holder and prescribing information.