Wednesday, July 8, 2026

Drug profile · INN

olaratumab

olaratumab (LARTRUVO) is a platelet-derived growth factor receptor alpha antagonist. Route of administration: injection. Current US regulatory status: approved.

FDA: approved EMA: unknown Antineoplastic and immunomodulating agents (L01) L01XC27
US status approved
Patents linked 0
Pipeline programs 2
News articles 0
Drug details — olaratumab
US status
approved
Class
Antineoplastic and immunomodulating agents (L01)
Route
INJECTION
Patents
0
Programs
2
Data quality
0.84

Quick answer

olaratumab (LARTRUVO) is a platelet-derived growth factor receptor alpha antagonist. Route of administration: injection. Current US regulatory status: approved.

Key facts

INN olaratumab
Brand LARTRUVO
Mechanism Platelet-derived growth factor receptor alpha antagonist
Target Platelet-derived growth factor receptor alpha
Therapeutic class Antineoplastic and immunomodulating agents (L01)
Route INJECTION
Formulation INJECTABLE
ATC code L01XC27

Mechanism of action

Platelet-derived growth factor receptor alpha antagonist

Primary target: Platelet-derived growth factor receptor alpha

Approval history

Authority Status Date
FDA approved
EMA unknown

Pipeline programs

  1. 89Zr-DFOsq-olaratumab (89Zr-TLX300-CDx) Phase 1 · Telix Innovations · Soft Tissue Sarcoma
  2. Olaratumab Phase 1 · Eli Lilly and · Malignancy

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. axitinib Antineoplastic and immunomodulating agents (L01)
  6. azacitidine Antineoplastic and immunomodulating agents (L01)

Frequently asked questions

What is olaratumab?

olaratumab (LARTRUVO) is a platelet-derived growth factor receptor alpha antagonist. Route of administration: injection. Current US regulatory status: approved.

What is the brand name for olaratumab?

LARTRUVO is a marketed brand name for olaratumab. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of olaratumab?

olaratumab has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.