Wednesday, July 8, 2026

Drug profile · INN

ofloxacin

ofloxacin (OCUFLOX) is a bacterial dna gyrase inhibitor. Associated with AbbVie. Route of administration: ophthalmic. Current US regulatory status: approved.

FDA: approved TGA: approved
US status approved
Patents linked 2
Pipeline programs 25
News articles 0
Drug details — ofloxacin
US status
approved
Class
Route
OPHTHALMIC
Patents
2
Programs
25
Data quality
0.89

Quick answer

ofloxacin (OCUFLOX) is a bacterial dna gyrase inhibitor. Associated with AbbVie. Route of administration: ophthalmic. Current US regulatory status: approved.

Key facts

INN ofloxacin
Brand OCUFLOX
Mechanism Bacterial DNA gyrase inhibitor
Target Bacterial DNA gyrase
Route OPHTHALMIC
Formulation INJECTABLE
Originator AbbVie

Mechanism of action

Bacterial DNA gyrase inhibitor

Primary target: Bacterial DNA gyrase

Approval history

Authority Status Date
FDA approved
TGA approved

Pipeline programs

  1. APHP220763 Phase 3 · PARItec · Catheter related bloodstream infections due to Staphylococcu
  2. APHP220814 Phase 3 · PARItec · Community-acquired pneumonia
  3. APHP241013 Phase 3 · PARItec · Young Adults and adults with R/R B-cell acute lymphoblastic
  4. Ciprofloxacin (BAYQ3939) dry powder for inhalation Phase 3 · Bayer HealthCare Animal · Bronchiectasis
  5. M14-671 Phase 3 · AbbVie Deutschland GmbH · Crohn's Disease (CD)
  6. NCT02735707 Phase 3 · Disc Medicine · Respiratory tract infection
  7. VACAB-2022 Phase 3 · George Institute for · Patients with hip or knee infections
  8. Vedolizumab-3041 Phase 3 · Takeda · Active Chronic Pouchitis

Related & competitor drugs

  1. cinoxacin Bacterial DNA gyrase inhibitor
  2. ciprofloxacin Bacterial DNA gyrase inhibitor
  3. ciprofloxacin hydrochloride Bacterial DNA gyrase inhibitor
  4. moxifloxacin hydrochloride Bacterial DNA gyrase inhibitor
  5. alatrofloxacin mesylate Bacterial DNA gyrase inhibitor
  6. besifloxacin hydrochloride Bacterial DNA gyrase inhibitor
  1. US 12097185

    Compositions comprising ciprofloxacin and celecoxib

    Expires Mon Sep 19 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 7629458

    Preparation of levofloxacin and hemihydrate thereof

    Expires Mon Dec 03 2029 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is ofloxacin?

ofloxacin (OCUFLOX) is a bacterial dna gyrase inhibitor. Associated with AbbVie. Route of administration: ophthalmic. Current US regulatory status: approved.

What is the brand name for ofloxacin?

OCUFLOX is a marketed brand name for ofloxacin. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of ofloxacin?

ofloxacin has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.