Saturday, July 11, 2026

Drug profile · INN

nirogacestat hydrobromide

nirogacestat hydrobromide (OGSIVEO) is a gamma-secretase inhibitor. Route of administration: oral. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 0
Pipeline programs 0
News articles 0
Drug details — nirogacestat hydrobromide
US status
approved
Class
Route
ORAL
Patents
0
Programs
0
Data quality
0.84

Quick answer

nirogacestat hydrobromide (OGSIVEO) is a gamma-secretase inhibitor. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN nirogacestat hydrobromide
Brand OGSIVEO
Mechanism Gamma-secretase inhibitor
Target Gamma-secretase
Route ORAL
Formulation TABLET

Mechanism of action

Gamma-secretase inhibitor

Primary target: Gamma-secretase

Approval history

Authority Status Date
FDA approved

Related & competitor drugs

  1. nirogacestat Antineoplastic and immunomodulating agents (L01)

Frequently asked questions

What is nirogacestat hydrobromide?

nirogacestat hydrobromide (OGSIVEO) is a gamma-secretase inhibitor. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for nirogacestat hydrobromide?

OGSIVEO is a marketed brand name for nirogacestat hydrobromide. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of nirogacestat hydrobromide?

nirogacestat hydrobromide has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.