Saturday, July 11, 2026

Drug profile · INN

nalfurafine hydrochloride

nalfurafine hydrochloride (NOPICOR) is a kappa opioid receptor agonist.

PMDA: approved
Patents linked 0
Pipeline programs 2
News articles 0
Drug details — nalfurafine hydrochloride
Class
Route
Patents
0
Programs
2
Data quality
0.78

Quick answer

nalfurafine hydrochloride (NOPICOR) is a kappa opioid receptor agonist.

Key facts

INN nalfurafine hydrochloride
Brand NOPICOR
Mechanism Kappa opioid receptor agonist
Target Kappa-type opioid receptor

Mechanism of action

Kappa opioid receptor agonist

Primary target: Kappa-type opioid receptor

Approval history

Authority Status Date
PMDA approved

Pipeline programs

  1. Nalfurafine Hydrochloride Phase 3 · Sunshine Guojian Pharmaceutical · Uremic Pruritus
  2. narfurine hydrochloride orally disintegrating tablets Phase 1 · First People's Hospital · Improvement of Pruritus in Hemodialysis Patients

Related & competitor drugs

  1. buprenorphine Nervous system (N07)
  2. buprenorphine hydrochloride Mu opioid receptor agonist
  3. anileridine hydrochloride Kappa opioid receptor agonist
  4. anileridine phosphate Kappa opioid receptor agonist
  5. butorphanol tartrate Kappa opioid receptor partial agonist
  6. dezocine Kappa opioid receptor antagonist

Frequently asked questions

What is nalfurafine hydrochloride?

nalfurafine hydrochloride (NOPICOR) is a kappa opioid receptor agonist.

What is the brand name for nalfurafine hydrochloride?

NOPICOR is a marketed brand name for nalfurafine hydrochloride. Check FDA Drugs@FDA for the current US label holder and prescribing information.