Friday, July 10, 2026

Drug profile · INN

methotrexate sodium

methotrexate sodium (METHOTREXATE SODIUM) is a dihydrofolate reductase inhibitor. Associated with Amneal Pharma Europe Ltd. Route of administration: injection. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 0
Pipeline programs 2
News articles 0
Drug details — methotrexate sodium
US status
approved
Class
Route
INJECTION
Patents
0
Programs
2
Data quality
0.89

Quick answer

methotrexate sodium (METHOTREXATE SODIUM) is a dihydrofolate reductase inhibitor. Associated with Amneal Pharma Europe Ltd. Route of administration: injection. Current US regulatory status: approved.

Key facts

INN methotrexate sodium
Brand METHOTREXATE SODIUM
Mechanism Dihydrofolate reductase inhibitor
Target Dihydrofolate reductase
Route INJECTION
Formulation INJECTABLE

Mechanism of action

Dihydrofolate reductase inhibitor

Primary target: Dihydrofolate reductase

Approval history

Authority Status Date
FDA approved

Pipeline programs

  1. 20190360 Phase 3 · Amgen · Newly diagnosed Philadelphia-negative B-cell precursor Acute
  2. SEVOFLURANE, DEXMEDETOMIDINE HYDROCHLORIDE Phase 3 · George Institute for · Children under the age of 2 years having surgery lasting at

Related & competitor drugs

  1. aminosalicylate sodium Dihydrofolate reductase inhibitor
  2. pemetrexed disodium Thymidylate synthase inhibitor
  3. pemetrexed sodium Thymidylate synthase inhibitor
  4. pralatrexate Antineoplastic and immunomodulating agents (L01)
  5. pyrimethamine Dihydrofolate reductase inhibitor
  6. trimethoprim Bacterial dihydrofolate reductase inhibitor

Frequently asked questions

What is methotrexate sodium?

methotrexate sodium (METHOTREXATE SODIUM) is a dihydrofolate reductase inhibitor. Associated with Amneal Pharma Europe Ltd. Route of administration: injection. Current US regulatory status: approved.

What is the brand name for methotrexate sodium?

METHOTREXATE SODIUM is a marketed brand name for methotrexate sodium. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of methotrexate sodium?

methotrexate sodium has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.