Friday, July 10, 2026

Drug profile · INN

methadone

methadone (METHADONE-AFT) is a mu opioid receptor agonist. Associated with Lacuna Pharma Pty Ltd.

TGA: approved
Patents linked 3
Pipeline programs 12
News articles 0
Drug details — methadone

Quick answer

methadone (METHADONE-AFT) is a mu opioid receptor agonist. Associated with Lacuna Pharma Pty Ltd.

Key facts

INN methadone
Brand METHADONE-AFT
Mechanism Mu opioid receptor agonist

Mechanism of action

Mu opioid receptor agonist

Approval history

Authority Status Date
TGA approved

Pipeline programs

  1. Methadone Phase 3 · BRIGHT MINDS BIOSCIENCES · Opioid-Related Disorders
  2. Methadone (100% dose) Phase 3 · BRIGHT MINDS BIOSCIENCES · Opioid Use Disorder
  3. Methadone Treatment-As-Usual Phase 3 · BRIGHT MINDS BIOSCIENCES · Opioid Use
  4. methadone Phase 3 · BRIGHT MINDS BIOSCIENCES · HIV
  5. Methadone Phase 2 · BRIGHT MINDS BIOSCIENCES · Cocaine-Related Disorders
  6. Methadone Phase 1 · BRIGHT MINDS BIOSCIENCES · Opiate-Related Disorders
  7. Pharmacy-based methadone administration and dispensing Phase 1 · BRIGHT MINDS BIOSCIENCES · Opioid-use Disorder
  8. METHADONE for Opioid use disorder (DSM-5); ch… Approved · Disc Medicine · Opioid use disorder (DSM-5); chronic non-cancer pain (ICD-11
  1. US 12384744

    Enzyme-cleavable methadone prodrugs and methods of use thereof

    Expires Mon Aug 07 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 9855226

    d-methadone for the treatment of psychiatric symptoms

    Expires Mon Dec 28 2037 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 9468611

    d-Methadone for the treatment of psychiatric symptoms

    Expires Mon Oct 13 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is methadone?

methadone (METHADONE-AFT) is a mu opioid receptor agonist. Associated with Lacuna Pharma Pty Ltd.

What is the brand name for methadone?

METHADONE-AFT is a marketed brand name for methadone. Check FDA Drugs@FDA for the current US label holder and prescribing information.