Wednesday, July 8, 2026

Drug profile · INN

mercaptopurine

mercaptopurine (ALLMERCAP) is a amidophosphoribosyltransferase inhibitor. Associated with Lacuna Pharma Pty Ltd. Route of administration: oral. Current US regulatory status: approved.

FDA: approved EMA: approved TGA: approved NMPA: clinical trials Antineoplastic and immunomodulating agents (L01) L01BB02
US status approved
Patents linked 5
Pipeline programs 10
News articles 0
Drug details — mercaptopurine
US status
approved
Class
Antineoplastic and immunomodulating agents (L01)
Route
ORAL
Patents
5
Programs
10
Data quality
0.84

Quick answer

mercaptopurine (ALLMERCAP) is a amidophosphoribosyltransferase inhibitor. Associated with Lacuna Pharma Pty Ltd. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN mercaptopurine
Brand ALLMERCAP
Mechanism Amidophosphoribosyltransferase inhibitor
Target Amidophosphoribosyltransferase
Therapeutic class Antineoplastic and immunomodulating agents (L01)
Route ORAL
Formulation SUSPENSION
ATC code L01BB02

Mechanism of action

Amidophosphoribosyltransferase inhibitor

Primary target: Amidophosphoribosyltransferase

Approval history

Authority Status Date
FDA approved
EMA approved
TGA approved
NMPA clinical trials

Pipeline programs

  1. 042011 Phase 3 · George Institute for · Langerhans Cell Histiocytosis
  2. 20190360 Phase 3 · Amgen · Newly diagnosed Philadelphia-negative B-cell precursor Acute
  3. ALL2820 Phase 3 · Telethon Foundation · Adult Philadelphia Chromosome-Positive Acute Lymphoblastic L
  4. 77242113UCO2001 Phase 2 · Janssen-Cilag International N.V · Ulcerative Colitis
  5. ALL2418 Phase 2 · Telethon Foundation · Acute B-cell Lymphoblastic Leukemia with minimal residual po
  6. Delayed Release 6 mercaptopurine Phase 2 · Teva Pharma · Crohn's Disease
  7. Delayed Release 6MP or Calcitriol vs. Purinethol Phase 2 · Teva Pharma · Crohn's Disease
  8. GIMEMA ALL2922 Phase 2 · Telethon Foundation · Adult Philadelphia Chromosome-Negative Acute Lymphoblastic L

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. axitinib Antineoplastic and immunomodulating agents (L01)
  6. azacitidine Antineoplastic and immunomodulating agents (L01)
  1. US 10590137

    Mercaptopurine hemihydrate

    Expires Mon Mar 12 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 9375403

    Formulations of 6-mercaptopurine

    Expires Mon Jun 23 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 9180097

    Formulations of 6-mercaptopurine

    Expires Mon Nov 05 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 8653060

    Formulations of 6-mercaptopurine

    Expires Mon Feb 13 2034 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 8188067

    Formulations of 6-mercaptopurine

    Expires Mon May 24 2032 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is mercaptopurine?

mercaptopurine (ALLMERCAP) is a amidophosphoribosyltransferase inhibitor. Associated with Lacuna Pharma Pty Ltd. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for mercaptopurine?

ALLMERCAP is a marketed brand name for mercaptopurine. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of mercaptopurine?

mercaptopurine has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.