Friday, July 10, 2026

Drug profile · INN

melphalan flufenamide

melphalan flufenamide (PEPAXTI) is an FDA-listed pharmaceutical active ingredient.

EMA: approved Antineoplastic and immunomodulating agents (L01) L01AA10
Patents linked 0
Pipeline programs 4
News articles 0
Drug details — melphalan flufenamide
Class
Antineoplastic and immunomodulating agents (L01)
Route
Patents
0
Programs
4
Data quality
0.83

Quick answer

melphalan flufenamide (PEPAXTI) is an FDA-listed pharmaceutical active ingredient.

Key facts

INN melphalan flufenamide
Brand PEPAXTI
Therapeutic class Antineoplastic and immunomodulating agents (L01)
ATC code L01AA10

Approval history

Authority Status Date
EMA approved

Pipeline programs

  1. Melflufen Phase 3 · Oncopeptides AB (publ) · Multiple Myeloma
  2. MELISSA Phase 2 · Telethon Foundation · Relapsed Multiple Myeloma
  3. Melphalan flufenamide (Melflufen) Phase 2 · Chongqing Precision Biotech · Multiple Myeloma
  4. NET-MS Phase 2 · Telethon Foundation · Relapsing Remitting Multiple Sclerosis

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. axitinib Antineoplastic and immunomodulating agents (L01)
  6. azacitidine Antineoplastic and immunomodulating agents (L01)

Frequently asked questions

What is melphalan flufenamide?

melphalan flufenamide (PEPAXTI) is an FDA-listed pharmaceutical active ingredient.

What is the brand name for melphalan flufenamide?

PEPAXTI is a marketed brand name for melphalan flufenamide. Check FDA Drugs@FDA for the current US label holder and prescribing information.