Friday, July 10, 2026

Drug profile · INN

lutetium (177lu) vipivotide tetraxetan

lutetium (177lu) vipivotide tetraxetan (PLUVICTO) is a dna disrupting agent.

EMA: approved Various (V10) V10XX
Patents linked 0
Pipeline programs 13
News articles 5
Drug details — lutetium (177lu) vipivotide tetraxetan

Quick answer

lutetium (177lu) vipivotide tetraxetan (PLUVICTO) is a dna disrupting agent.

Key facts

INN lutetium (177lu) vipivotide tetraxetan
Brand PLUVICTO
Mechanism DNA disrupting agent
Target DNA
Therapeutic class Various (V10)
ATC code V10XX

Mechanism of action

DNA disrupting agent

Primary target: DNA

Approval history

Authority Status Date
EMA approved

Recent coverage

Truqap gains US approval in PTEN-deficient metastatic prostate cancer
High impact Newsprostate cancerJun 13, 2026

Truqap gains US approval in PTEN-deficient metastatic prostate cancer

FDA · prostate cancer · 6 min

AstraZeneca’s Truqap (capivasertib) has been approved in the US with abiraterone and prednisone for PTEN-deficient metastatic prostate cancer. The move creates a first-in-class targeted option and a new catalyst to watch for BD teams, investors, and analysts.

Dr. Elena Rossi
New Radiopharmaceutical Shows Promise in Post-Pluvicto Setting, Offering Competitive Insights
High impact AnalysisJun 2, 2026

New Radiopharmaceutical Shows Promise in Post-Pluvicto Setting, Offering Competitive Insights

9 min

A novel radiopharmaceutical is demonstrating promising results in patients who have previously been treated with Pluvicto, signaling a potential shift in the advanced prostate cancer treatment paradigm. This development presents significant competitive implications for companies like Abivax, Fulcrum, Convergent, and Vera.

Dr. Sarah Mitchell
Novartis Strengthens Prostate Cancer Treatment with Pluvicto
Medium impact NewsoncologyMay 21, 2026

Novartis Strengthens Prostate Cancer Treatment with Pluvicto

oncology · 2 min

Novartis has reported stronger PSA responses with its drug Pluvicto in earlier-stage prostate cancer, indicating promising developments in oncology. This news could reshape competitive dynamics in the market.

Dr. Yuki Tanaka
Radioligand Therapies for Prostate Cancer: Market Access and Clinical Insights in APAC
High impact AnalysisoncologyApr 21, 2026

Radioligand Therapies for Prostate Cancer: Market Access and Clinical Insights in APAC

NMPA · oncology · 12 min

This article delves into the landscape of radioligand therapies for prostate cancer, focusing on market access and clinical insights across the APAC region.

Dr. Yuki Tanaka

Pipeline programs

  1. CAAA617B12302 Phase 3 · Novartis India · PSMA-positive metastatic castration-resistant prostate cance
  2. CAAA617C12301 Phase 3 · Novartis India · PSMA-positive metastatic hormone-sensitive prostate cancer (
  3. CAAA617D12302 Phase 3 · Novartis India · Oligometastatic prostate cancer (OMPC)
  4. UC-GTG-2301 Phase 3 · Ningbo Cancer Hospital · Novo metastatic hormone-sensitive prostate cancer (mHSPC) pa
  5. 177Lu-PSMA-617 Phase 2 · United Therapeutics Europe · Metastatic Hormone Naive Prostate Cancer
  6. CAAA617A12202 Phase 2 · Novartis India · Progressive PSMA-Positive Metastatic Castration-Resistant Pr
  7. CAAA617B12203 Phase 2 · Novartis India · PSMA PET scan positive Castration-Resistant Prostate Cancer
  8. CAMO959A12103 Phase 2 · Novartis India · PSMA-positive mCRPC with prior exposure to at least one prio

Related & competitor drugs

  1. acyclovir Human herpesvirus 1 DNA polymerase inhibitor
  2. acyclovir sodium Human herpesvirus 1 DNA polymerase inhibitor
  3. azacitidine Antineoplastic and immunomodulating agents (L01)
  4. besilesomab Various (V09)
  5. bleomycin sulfate DNA inhibitor
  6. busulfan Antineoplastic and immunomodulating agents (L01)

Frequently asked questions

What is lutetium (177lu) vipivotide tetraxetan?

lutetium (177lu) vipivotide tetraxetan (PLUVICTO) is a dna disrupting agent.

What is the brand name for lutetium (177lu) vipivotide tetraxetan?

PLUVICTO is a marketed brand name for lutetium (177lu) vipivotide tetraxetan. Check FDA Drugs@FDA for the current US label holder and prescribing information.