Friday, July 10, 2026

Drug profile · INN

loncastuximab tesirine

loncastuximab tesirine (ZYNLONTA) is a b-lymphocyte antigen cd19 binding agent.

EMA: approved Antineoplastic and immunomodulating agents (L01) L01FX22
Patents linked 0
Pipeline programs 15
News articles 0
Drug details — loncastuximab tesirine
Class
Antineoplastic and immunomodulating agents (L01)
Route
Patents
0
Programs
15
Data quality
0.83

Quick answer

loncastuximab tesirine (ZYNLONTA) is a b-lymphocyte antigen cd19 binding agent.

Key facts

INN loncastuximab tesirine
Brand ZYNLONTA
Mechanism B-lymphocyte antigen CD19 binding agent
Target B-lymphocyte antigen CD19
Therapeutic class Antineoplastic and immunomodulating agents (L01)
ATC code L01FX22

Mechanism of action

B-lymphocyte antigen CD19 binding agent

Primary target: B-lymphocyte antigen CD19

Approval history

Authority Status Date
EMA approved

Pipeline programs

  1. Loncastuximab Tesirine Phase 3 · ADC Therapeutics · Relapsed Diffuse Large B-Cell Lymphoma
  2. FIL_COLUMN Phase 2 · Telethon Foundation · Mantle cell lymphoma
  3. Loncastuximab Tesirine Phase 2 · ADC Therapeutics · Waldenstrom Macroglobulinemia
  4. Loncastuximab Tesirine Phase 2 · ADC Therapeutics · Relapsed or Refractory Large B-cell Lymphoma
  5. Loncastuximab Tesirine Phase 2 · ADC Therapeutics · Diffuse Large B-cell Lymphoma
  6. Loncastuximab Tesirine Phase 2 · ADC Therapeutics · Relapsed Follicular Lymphoma
  7. Loncastuximab tesirine Phase 2 · ADC Therapeutics · Diffuse Large B-Cell Lymphoma Refractory
  8. Loncastuximab tesirine Phase 2 · ADC Therapeutics · Post-transplant Lymphoproliferative Disorder

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. axitinib Antineoplastic and immunomodulating agents (L01)
  6. azacitidine Antineoplastic and immunomodulating agents (L01)

Frequently asked questions

What is loncastuximab tesirine?

loncastuximab tesirine (ZYNLONTA) is a b-lymphocyte antigen cd19 binding agent.

What is the brand name for loncastuximab tesirine?

ZYNLONTA is a marketed brand name for loncastuximab tesirine. Check FDA Drugs@FDA for the current US label holder and prescribing information.