Wednesday, July 8, 2026

Drug profile · INN

lonafarnib

lonafarnib (ZOKINVY) is a protein farnesyltransferase inhibitor. Route of administration: oral. Current US regulatory status: approved.

FDA: approved EMA: approved
US status approved
Patents linked 1
Pipeline programs 0
News articles 0
Drug details — lonafarnib
US status
approved
Class
Route
ORAL
Patents
1
Programs
0
Data quality
0.84

Quick answer

lonafarnib (ZOKINVY) is a protein farnesyltransferase inhibitor. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN lonafarnib
Brand ZOKINVY
Mechanism Protein farnesyltransferase inhibitor
Target Protein farnesyltransferase
Route ORAL
Formulation CAPSULE

Mechanism of action

Protein farnesyltransferase inhibitor

Primary target: Protein farnesyltransferase

Approval history

Authority Status Date
FDA approved
EMA approved

Related patents

  1. US 7838531

    Farnesyltransferase inhibitors for treatment of laminopathies, cellular aging and atherosclerosis

    Expires Mon Nov 18 2030 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is lonafarnib?

lonafarnib (ZOKINVY) is a protein farnesyltransferase inhibitor. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for lonafarnib?

ZOKINVY is a marketed brand name for lonafarnib. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of lonafarnib?

lonafarnib has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.