Friday, July 10, 2026

Drug profile · INN

lifileucel

lifileucel (AMTAGVI) is a somatic cell supplemental therapy. Associated with Iovance Biotherapeutics B.V..

EMA: application withdrawn Antineoplastic and immunomodulating agents (L01) L01XL11
Patents linked 3
Pipeline programs 8
News articles 0
Drug details — lifileucel
Class
Antineoplastic and immunomodulating agents (L01)
Route
Patents
3
Programs
8
Data quality
0.89

Quick answer

lifileucel (AMTAGVI) is a somatic cell supplemental therapy. Associated with Iovance Biotherapeutics B.V..

Key facts

INN lifileucel
Brand AMTAGVI
Mechanism Somatic cell supplemental therapy
Therapeutic class Antineoplastic and immunomodulating agents (L01)
ATC code L01XL11

Mechanism of action

Somatic cell supplemental therapy

Approval history

Authority Status Date
EMA application withdrawn

Pipeline programs

  1. Lifileucel plus Pembrolizumab Phase 3 · Iovance Biotherapeutics · Metastatic Melanoma
  2. IOV-COM-202 Phase 2 · Iovance Biotherapeutics · Neoplasm
  3. IOV-MEL-202 Phase 2 · Iovance Biotherapeutics · Previously treated advanced melanoma
  4. Lifileucel Phase 2 · Iovance Biotherapeutics · Melanoma (Skin Cancer)
  5. Lifileucel Phase 2 · Iovance Biotherapeutics · Metastatic Melanoma
  6. Lifileucel Phase 2 · Iovance Biotherapeutics · Endometrial Cancer
  7. Lifileucel (LN-144) Phase 1 · Iovance Biotherapeutics · Metastatic Melanoma
  8. Lifileucel (LN-144/LN-145) Phase 1 · Iovance Biotherapeutics · Uveal Melanoma

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. axitinib Antineoplastic and immunomodulating agents (L01)
  6. azacitidine Antineoplastic and immunomodulating agents (L01)
  1. US 10004806

    Periodontal regeneration composition and method of using same

    Expires Mon Jun 21 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 9556146

    Lanthionine synthetase C-like 2-based therapeutics

    Expires Mon Jan 26 2037 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 6670148

    Compositions comprising bioactive peptides prepared without formation of native disulfide bonds

    Expires Mon Dec 25 2023 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired

Frequently asked questions

What is lifileucel?

lifileucel (AMTAGVI) is a somatic cell supplemental therapy. Associated with Iovance Biotherapeutics B.V..

What is the brand name for lifileucel?

AMTAGVI is a marketed brand name for lifileucel. Check FDA Drugs@FDA for the current US label holder and prescribing information.