Saturday, July 11, 2026

Drug profile · INN

lepirudin

lepirudin (REFLUDAN) is a thrombin inhibitor.

EMA: withdrawn Blood and blood forming organs (B01) B01AE02
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Drug details — lepirudin
Class
Blood and blood forming organs (B01)
Route
Patents
0
Programs
0
Data quality
0.83

Quick answer

lepirudin (REFLUDAN) is a thrombin inhibitor.

Key facts

INN lepirudin
Brand REFLUDAN
Mechanism Thrombin inhibitor
Target Prothrombin
Therapeutic class Blood and blood forming organs (B01)
ATC code B01AE02

Mechanism of action

Thrombin inhibitor

Primary target: Prothrombin

Approval history

Authority Status Date
EMA withdrawn

Related & competitor drugs

  1. apixaban Blood and blood forming organs (B01)
  2. argatroban Thrombin inhibitor
  3. berotralstat Blood and blood forming organs (B06)
  4. bivalirudin Blood and blood forming organs (B01)
  5. c1 inhibitor (human) Blood and blood forming organs (B06)
  6. clopidogrel Blood and blood forming organs (B01)

Frequently asked questions

What is lepirudin?

lepirudin (REFLUDAN) is a thrombin inhibitor.

What is the brand name for lepirudin?

REFLUDAN is a marketed brand name for lepirudin. Check FDA Drugs@FDA for the current US label holder and prescribing information.