Friday, July 10, 2026

Drug profile · INN

lapatinib

lapatinib (TYKERB) is a receptor protein-tyrosine kinase erbb-2 inhibitor. Associated with Novartis Pharmaceuticals.

EMA: approved TGA: approved Antineoplastic and immunomodulating agents (L01) L01EH01
Patents linked 0
Pipeline programs 8
News articles 0
Drug details — lapatinib
Class
Antineoplastic and immunomodulating agents (L01)
Route
Patents
0
Programs
8
Data quality
0.83

Quick answer

lapatinib (TYKERB) is a receptor protein-tyrosine kinase erbb-2 inhibitor. Associated with Novartis Pharmaceuticals.

Key facts

INN lapatinib
Brand TYKERB
Mechanism Receptor protein-tyrosine kinase erbB-2 inhibitor
Therapeutic class Antineoplastic and immunomodulating agents (L01)
ATC code L01EH01

Mechanism of action

Receptor protein-tyrosine kinase erbB-2 inhibitor

Approval history

Authority Status Date
EMA approved
TGA approved

Pipeline programs

  1. C16-40 Phase 3 · George Institute for · Unresectable locally advanced and/or metastatic soft-tissue
  2. Lapatinib Phase 3 · Novartis India · Breast Neoplasms
  3. Lapatinib Phase 3 · GSK Glaxo Smith · Neoplasms, Head and Neck
  4. Lapatinib Phase 3 · Novartis India · Neoplasms, Breast
  5. lapatinib Phase 3 · GSK Glaxo Smith · Neoplasms, Breast
  6. Lapatinib Phase 2 · United Therapeutics Europe · Breast Cancer
  7. Mektovi film-coated tablets for metastatic colorectal cancer wi… Phase 2 · Disc Medicine · metastatic colorectal cancer with a proven RAS mutation afte
  8. paclitaxel/carboplatin/lapatinib Phase 2 · Hospital Authority · ErbB2-Positive Stage I-III Breast Cancer

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. axitinib Antineoplastic and immunomodulating agents (L01)
  6. azacitidine Antineoplastic and immunomodulating agents (L01)

Frequently asked questions

What is lapatinib?

lapatinib (TYKERB) is a receptor protein-tyrosine kinase erbb-2 inhibitor. Associated with Novartis Pharmaceuticals.

What is the brand name for lapatinib?

TYKERB is a marketed brand name for lapatinib. Check FDA Drugs@FDA for the current US label holder and prescribing information.