Friday, July 10, 2026

Drug profile · INN

ixazomib

ixazomib (NINLARO) is a 26s proteasome inhibitor. Associated with Takeda.

EMA: approved NMPA: clinical trials Antineoplastic and immunomodulating agents (L01) L01XG03
Patents linked 0
Pipeline programs 34
News articles 0
Drug details — ixazomib
Class
Antineoplastic and immunomodulating agents (L01)
Route
Patents
0
Programs
34
Data quality
0.89

Quick answer

ixazomib (NINLARO) is a 26s proteasome inhibitor. Associated with Takeda.

Key facts

INN ixazomib
Brand NINLARO
Mechanism 26S proteasome inhibitor
Target 26S proteasome
Therapeutic class Antineoplastic and immunomodulating agents (L01)
ATC code L01XG03
Originator Takeda

Mechanism of action

26S proteasome inhibitor

Primary target: 26S proteasome

Approval history

Authority Status Date
EMA approved
NMPA clinical trials

Pipeline programs

  1. BB2121-MM-003 Phase 3 · Celgene · Multiple myeloma (MM) with at least 2 prior therapies includ
  2. HM16/047 Phase 3 · Takeda · Multiple Myeloma
  3. IXAZOMIB Phase 3 · Takeda · Relapsed or Refractory Systemic Light Chain Amyloidosis
  4. Ixazomib Phase 3 · Takeda · Relapsed Multiple Myeloma
  5. Ixazomib Citrate Phase 3 · Takeda · Multiple Myeloma
  6. MyelomaXIV Phase 3 · Takeda · Multiple Myeloma
  7. IXAZOMIB Phase 2 · Takeda · Follicular Lymphoma
  8. Ixazomib Phase 2 · Takeda · Multiple Myeloma

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. axitinib Antineoplastic and immunomodulating agents (L01)
  6. azacitidine Antineoplastic and immunomodulating agents (L01)

Frequently asked questions

What is ixazomib?

ixazomib (NINLARO) is a 26s proteasome inhibitor. Associated with Takeda.

What is the brand name for ixazomib?

NINLARO is a marketed brand name for ixazomib. Check FDA Drugs@FDA for the current US label holder and prescribing information.