Friday, July 10, 2026

Drug profile · INN

isatuximab

isatuximab (SARCLISA) is a lymphocyte differentiation antigen cd38 inhibitor.

EMA: approved PMDA: approved NMPA: clinical trials Antineoplastic and immunomodulating agents (L01) L01XC38
Patents linked 0
Pipeline programs 21
News articles 0
Drug details — isatuximab
Class
Antineoplastic and immunomodulating agents (L01)
Route
Patents
0
Programs
21
Data quality
0.83

Quick answer

isatuximab (SARCLISA) is a lymphocyte differentiation antigen cd38 inhibitor.

Key facts

INN isatuximab
Brand SARCLISA
Mechanism Lymphocyte differentiation antigen CD38 inhibitor
Target ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
Therapeutic class Antineoplastic and immunomodulating agents (L01)
ATC code L01XC38

Mechanism of action

Lymphocyte differentiation antigen CD38 inhibitor

Primary target: ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1

Approval history

Authority Status Date
EMA approved
PMDA approved
NMPA clinical trials

Pipeline programs

  1. EFC12522 Phase 3 · Sanofi-Aventis U.S · Cancer
  2. EFC15951 Phase 3 · Sanofi-Aventis U.S · Cancer - Plasma cell myeloma recurrent
  3. EFC15992 Phase 3 · Sanofi-Aventis U.S · Plasma cell myeloma
  4. Isatuximab SAR650984 Phase 3 · Sanofi Pasteur MSD · Plasma Cell Myeloma
  5. SARCLISA for Patients aged 18-65 years old w… Phase 3 · PARItec · Patients aged 18-65 years old with newly diagnosed previousl
  6. 208887 Phase 2 · GSK Glaxo Smith · Multiple Myeloma
  7. ACT16482-01 Phase 2 · Sanofi-Aventis U.S · Cancer
  8. ACT16482-03 Phase 2 · Sanofi-Aventis U.S · Cancer

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. axitinib Antineoplastic and immunomodulating agents (L01)
  6. azacitidine Antineoplastic and immunomodulating agents (L01)

Frequently asked questions

What is isatuximab?

isatuximab (SARCLISA) is a lymphocyte differentiation antigen cd38 inhibitor.

What is the brand name for isatuximab?

SARCLISA is a marketed brand name for isatuximab. Check FDA Drugs@FDA for the current US label holder and prescribing information.