Saturday, July 11, 2026

Drug profile · INN

irinotecan

irinotecan (IRINOTECAN ACCORD) is a dna topoisomerase i inhibitor. Associated with BAXTER HEALTHCARE PTY LTD.

TGA: approved NMPA: clinical trials
Patents linked 1
Pipeline programs 79
News articles 0
Drug details — irinotecan

Quick answer

irinotecan (IRINOTECAN ACCORD) is a dna topoisomerase i inhibitor. Associated with BAXTER HEALTHCARE PTY LTD.

Key facts

INN irinotecan
Brand IRINOTECAN ACCORD
Mechanism DNA topoisomerase I inhibitor

Mechanism of action

DNA topoisomerase I inhibitor

Approval history

Authority Status Date
TGA approved
NMPA clinical trials

Pipeline programs

  1. 20210081 Phase 3 · Amgen · Colorectal Cancer (CRC)
  2. APHP220917 Phase 3 · PARItec · patient with colorectal cancer with hepatic metastasis
  3. C4221015 Phase 3 · First Biotech (Australia) · Colorectal cancer (BRAF V600E-mutant mCRC)
  4. CA209-8HW Phase 3 · Bristol-Myers Squibb Australia · Microsatellite Instability High (MSI-H) or Mismatch Repair D
  5. CA2660003 Phase 3 · Bristol-Myers Squibb Australia · Untreated, Unresectable or Metastatic Colorectal Cancer
  6. D9802C00001 Phase 3 · AstraZeneca · Gastric cancer, Advanced/Metastatic Gastric cancer, Gastroes
  7. DS7300-202 Phase 3 · Daiichi Sankyo US · Esophageal Squamous Cell Carcinoma (ESCC)
  8. GCO-003 TARLANEC Phase 3 · CERo Therapeutics · Advanced pulmonary or gastroenteropancreatic poorly differen
  1. US 6881420

    Compositions and dosage forms for gastric delivery of irinotecan and methods of treatment that use it to inhibit cancer cell proliferation

    Expires Mon Apr 14 2025 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired

Frequently asked questions

What is irinotecan?

irinotecan (IRINOTECAN ACCORD) is a dna topoisomerase i inhibitor. Associated with BAXTER HEALTHCARE PTY LTD.

What is the brand name for irinotecan?

IRINOTECAN ACCORD is a marketed brand name for irinotecan. Check FDA Drugs@FDA for the current US label holder and prescribing information.