Friday, July 10, 2026

Drug profile · INN

imetelstat

imetelstat (RYTELO) is a telomerase reverse transcriptase inhibitor.

EMA: approved Antineoplastic and immunomodulating agents (L01) L01XX80
Patents linked 0
Pipeline programs 3
News articles 0
Drug details — imetelstat
Class
Antineoplastic and immunomodulating agents (L01)
Route
Patents
0
Programs
3
Data quality
0.83

Quick answer

imetelstat (RYTELO) is a telomerase reverse transcriptase inhibitor.

Key facts

INN imetelstat
Brand RYTELO
Mechanism Telomerase reverse transcriptase inhibitor
Target Telomerase reverse transcriptase
Therapeutic class Antineoplastic and immunomodulating agents (L01)
ATC code L01XX80

Mechanism of action

Telomerase reverse transcriptase inhibitor

Primary target: Telomerase reverse transcriptase

Approval history

Authority Status Date
EMA approved

Pipeline programs

  1. 63935937MDS3001 Phase 3 · Geron Netherlands · Myelodysplastic syndromes (MDS)
  2. GRN163LMYF3001 Phase 3 · Geron Netherlands · Myelofibrosis
  3. Imetelstat Phase 3 · Geron Netherlands · Myelofibrosis

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. axitinib Antineoplastic and immunomodulating agents (L01)
  6. azacitidine Antineoplastic and immunomodulating agents (L01)

Frequently asked questions

What is imetelstat?

imetelstat (RYTELO) is a telomerase reverse transcriptase inhibitor.

What is the brand name for imetelstat?

RYTELO is a marketed brand name for imetelstat. Check FDA Drugs@FDA for the current US label holder and prescribing information.