Wednesday, July 8, 2026

Drug profile · INN

hexachlorophene

hexachlorophene (SOY-DOME) is a bacterial enoyl-[acyl-carrier-protein] reductase inhibitor. Associated with ADIAL PHARMACEUTICALS, INC.. Route of administration: topical. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 20
Pipeline programs 94
News articles 0
Drug details — hexachlorophene
US status
approved
Class
Route
TOPICAL
Patents
20
Programs
94
Data quality
0.89

Quick answer

hexachlorophene (SOY-DOME) is a bacterial enoyl-[acyl-carrier-protein] reductase inhibitor. Associated with ADIAL PHARMACEUTICALS, INC.. Route of administration: topical. Current US regulatory status: approved.

Key facts

INN hexachlorophene
Brand SOY-DOME
Mechanism Bacterial enoyl-[acyl-carrier-protein] reductase inhibitor
Target Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Route TOPICAL
Formulation SOLUTION

Mechanism of action

Bacterial enoyl-[acyl-carrier-protein] reductase inhibitor

Primary target: Enoyl-[acyl-carrier-protein] reductase [NADH] FabI

Approval history

Authority Status Date
FDA approved

Pipeline programs

  1. 20170724 Phase 3 · Amgen · Secondary hyperparathyroidism (SHPT) in pediatric patients w
  2. APHP 180610 Phase 3 · PARItec · Acute Myocardial Infarction
  3. APHP 180610 Phase 3 · PARItec · Acute Myocardial Infarction
  4. APHP180560 Phase 3 · PARItec · Men and women over 18 years of age with renal failure renal
  5. APHP230855 Phase 3 · PARItec · Patients presenting with acute myocarditis proven by cardiac
  6. Alirocumab 150 MG/ML [Praluent] Phase 3 · Regeneron UK · Hemodialysis
  7. Auto-CD34+ cells Phase 3 · Lisata Therapeutics · Chronic Myocardial Ischemia
  8. Autologous Peripheral Blood Stem Cell injection Phase 3 · Hospital Authority · Acute Myocardial Infarction
  1. US 12351653

    Pharmaceutical compositions comprising novel cyclic peptides

    Expires Mon Jul 03 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 12162837

    Substituted 3-dialkylaminomethyl-piperidin-4-yl-benzamides and methods of making and using same

    Expires Mon Dec 05 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 12059418

    Plasmodial surface anion channel inhibitors for the treatment or prevention of malaria

    Expires Mon Aug 08 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11884932

    In vitro production of medial ganglionic eminence precursor cells

    Expires Mon Jan 25 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 11851503

    Antiplasmodial compounds

    Expires Mon Dec 21 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 11725217

    Methods to enhance myocardial regeneration and/or repair

    Expires Mon Aug 10 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 11530240

    Catheter injectable cyclic peptide pro-gelators for myocardial tissue engineering

    Expires Mon Dec 15 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 11319290

    Substituted 3-dialkylaminomethyl-piperidin-4-yl-benzamides and methods of making and using same

    Expires Mon Apr 28 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 11230569

    Antiplasmodial compounds

    Expires Mon Jan 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 11141496

    Use of berberine or derivative thereof in preparing myocardial perfusion imaging agent

    Expires Mon Oct 07 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10927135

    Metal-free direct arylation of dialkyl phosphonates for the synthesis of mixed alkyl aryl phosphonates

    Expires Mon Feb 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10881669

    Inhibitors of the plasmodial surface anion channel as antimalarials

    Expires Mon Dec 31 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10869865

    Plasmodial surface anion channel inhibitors for the treatment or prevention of malaria

    Expires Mon Dec 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10836728

    Substituted 3-dialkylaminomethyl-piperidin-4-yl-benzamides and methods of making and using same

    Expires Mon Nov 12 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10760048

    In vitro production of medial ganglionic eminence precursor cells

    Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10682416

    Epicardial-derived paracrine factors for repairing cardiac tissue

    Expires Mon Jun 11 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10639289

    Application of neuraminidase and inhibitors thereof in myocardial ischemia and myocardial infarction

    Expires Mon Apr 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10265313

    Plasmodial surface anion channel inhibitors for the treatment or prevention of malaria

    Expires Mon Apr 18 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10100279

    In vitro production of medial ganglionic eminence precursor cells

    Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 9974796

    Inhibitors of the plasmodial surface anion channel as antimalarials

    Expires Mon May 17 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is hexachlorophene?

hexachlorophene (SOY-DOME) is a bacterial enoyl-[acyl-carrier-protein] reductase inhibitor. Associated with ADIAL PHARMACEUTICALS, INC.. Route of administration: topical. Current US regulatory status: approved.

What is the brand name for hexachlorophene?

SOY-DOME is a marketed brand name for hexachlorophene. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of hexachlorophene?

hexachlorophene has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.