Wednesday, July 8, 2026

Drug profile · INN

glucagon hydrochloride

glucagon hydrochloride (GLUCAGEN HYPOKIT) is a glucagon receptor agonist. Associated with NovoThirteen. Route of administration: intramuscular, intravenous, subcutaneous. Current US regulatory status: approved.

FDA: approved TGA: approved
US status approved
Patents linked 20
Pipeline programs 19
News articles 0
Drug details — glucagon hydrochloride
US status
approved
Class
Route
INTRAMUSCULAR, INTRAVENOUS, SUBCUTANEOUS
Patents
20
Programs
19
Data quality
0.84

Quick answer

glucagon hydrochloride (GLUCAGEN HYPOKIT) is a glucagon receptor agonist. Associated with NovoThirteen. Route of administration: intramuscular, intravenous, subcutaneous. Current US regulatory status: approved.

Key facts

INN glucagon hydrochloride
Brand GLUCAGEN HYPOKIT
Mechanism Glucagon receptor agonist
Target Glucagon receptor
Route INTRAMUSCULAR, INTRAVENOUS, SUBCUTANEOUS
Formulation INJECTABLE
Originator NovoThirteen

Mechanism of action

Glucagon receptor agonist

Primary target: Glucagon receptor

Approval history

Authority Status Date
FDA approved
TGA approved

Pipeline programs

  1. Dasiglucagon 4 mg/ml Phase 3 · Zealand Pharma · Children with congenital hyperinsulinism
  2. G-Pen (glucagon injection) Phase 3 · Xeris Biopharma Holdings · Hypoglycemia
  3. Glucagon Phase 3 · Xeris Biopharma Holdings · Diabetes Mellitus, Type 1
  4. [18F]-AlF-FAPI-74 for Cholangiocarcinoma Phase 3 · Disc Medicine · Cholangiocarcinoma
  5. D8460C00004 Phase 2 · AstraZeneca · Investigating obesity or overweight condition correlated to
  6. G-Pen Mini™ (glucagon injection) Phase 2 · Xeris Biopharma Holdings · Hypoglycemia
  7. G-Pen Mini™ (glucagon injection) Phase 2 · Xeris Biopharma Holdings · Diabetes Mellitus, Type 1
  8. G-Pump™ (glucagon infusion) Phase 2 · Xeris Biopharma Holdings · Hypoglycemia

Related & competitor drugs

  1. glucagon Systemic hormonal preparations (H04)
  2. dasiglucagon hydrochloride Glucagon receptor agonist
  3. dasiglucagon Systemic hormonal preparations (H04)
  4. efinopegdutide Glucagon-like peptide 1 receptor agonist
  1. WO 2025252715

    AGONISTE DOUBLE DU RÉCEPTEUR DU GLP-1 ET DU GLUCAGON POUR LE TRAITEMENT DE LA MASH ET DE LA CIRRHOSE

    Expires Wed Dec 06 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 12421317

    Polynucleotides encoding anti-glucagon-like peptide 1 receptor (GLP1R) antagonist antibodies

    Expires Mon Sep 18 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 12370241

    Nasal powder formulation for treatment of hypoglycemia

    Expires Mon Jul 24 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 12269889

    Human antibodies to the human glucagon receptor (HGCGR) and methods of use thereof to lower blood glucose or ketone levels

    Expires Mon Apr 03 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 12208071

    Glucagon receptor antagonists

    Expires Mon Jan 23 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 12139546

    Methods of treating urea cycle disorders by interfering with glucagon receptor signaling

    Expires Mon Nov 07 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 12090193

    Glucagon-like peptide 1 receptor agonists and uses thereof

    Expires Mon Sep 12 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 11951176

    Stabilization of glucagon by trehalose glycopolymer nanogels

    Expires Mon Apr 04 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 11884736

    Antibodies which bind to glucagon-like peptide 1 receptor (GLP1R)

    Expires Mon Jan 25 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 11779633

    Glucagon-like peptide 1 receptor agonists and uses thereof

    Expires Mon Oct 05 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 11708416

    Methods of treating severe insulin resistance by interfering with glucagon receptor signaling

    Expires Mon Jul 20 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 11590205

    Methods for producing stable therapeutic glucagon formulations in aprotic polar solvents

    Expires Mon Feb 23 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 11498970

    Human antibodies to the human glucagon receptor and methods of use thereof to lower blood glucose or ketone levels

    Expires Mon Nov 10 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 11045522

    Glucagon-like peptide 1 receptor agonists and uses thereof

    Expires Mon Jun 24 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10995146

    Methods of treating severe insulin resistance by interfering with glucagon receptor signaling

    Expires Mon Apr 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10640566

    Nucleic acid molecules encoding antibodies to the human glucagon receptor

    Expires Mon Apr 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10233250

    Human antibodies to the glucagon receptor and methods of use thereof for lowering blood glucose or ketone levels

    Expires Mon Mar 14 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 9687527

    Stable glucagon formulations for the treatment of hypoglycemia

    Expires Mon Jun 22 2037 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 9657099

    Anti-glucagon antibodies

    Expires Mon May 18 2037 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 9649364

    Methods for producing stable therapeutic formulations in aprotic polar solvents

    Expires Mon May 11 2037 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is glucagon hydrochloride?

glucagon hydrochloride (GLUCAGEN HYPOKIT) is a glucagon receptor agonist. Associated with NovoThirteen. Route of administration: intramuscular, intravenous, subcutaneous. Current US regulatory status: approved.

What is the brand name for glucagon hydrochloride?

GLUCAGEN HYPOKIT is a marketed brand name for glucagon hydrochloride. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of glucagon hydrochloride?

glucagon hydrochloride has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.