Saturday, July 11, 2026

Drug profile · INN

gefapixant

gefapixant (LYFNUA) is a p2x purinoceptor 3 antagonist.

EMA: approved Respiratory system (R05) R05DB29
Patents linked 0
Pipeline programs 0
News articles 0
Drug details — gefapixant
Class
Respiratory system (R05)
Route
Patents
0
Programs
0
Data quality
0.83

Quick answer

gefapixant (LYFNUA) is a p2x purinoceptor 3 antagonist.

Key facts

INN gefapixant
Brand LYFNUA
Mechanism P2X purinoceptor 3 antagonist
Target P2X purinoceptor 3
Therapeutic class Respiratory system (R05)
ATC code R05DB29

Mechanism of action

P2X purinoceptor 3 antagonist

Primary target: P2X purinoceptor 3

Approval history

Authority Status Date
EMA approved

Related & competitor drugs

  1. desloratadine Respiratory system (R01)
  2. deutivacaftor / tezacaftor / vanzacaftor Respiratory system (R07)
  3. ivacaftor Respiratory system (R07)
  4. lumacaftor Respiratory system (R07)
  5. mannitol Respiratory system (R05)
  6. reslizumab Respiratory system (R03)

Frequently asked questions

What is gefapixant?

gefapixant (LYFNUA) is a p2x purinoceptor 3 antagonist.

What is the brand name for gefapixant?

LYFNUA is a marketed brand name for gefapixant. Check FDA Drugs@FDA for the current US label holder and prescribing information.