Friday, July 10, 2026

Drug profile · INN

ex vivo expanded autologous human corneal epithelial cells containing stem cells

ex vivo expanded autologous human corneal epithelial cells containing stem cells (HOLOCLAR) is a somatic cell supplemental therapy.

EMA: approved Sensory organs (S01) S01XA19
Patents linked 0
Pipeline programs 3
News articles 0
Drug details — ex vivo expanded autologous human corneal epithelial cells containing stem cells
Class
Sensory organs (S01)
Route
Patents
0
Programs
3
Data quality
0.83

Quick answer

ex vivo expanded autologous human corneal epithelial cells containing stem cells (HOLOCLAR) is a somatic cell supplemental therapy.

Key facts

INN ex vivo expanded autologous human corneal epithelial cells containing stem cells
Brand HOLOCLAR
Mechanism Somatic cell supplemental therapy
Therapeutic class Sensory organs (S01)
ATC code S01XA19

Mechanism of action

Somatic cell supplemental therapy

Approval history

Authority Status Date
EMA approved

Pipeline programs

  1. Stem cells Phase 2 · Takeda · Rheumatoid Arthritis Aggravated
  2. Stem Cell Phase 1 · UroGen Pharma · Neurological; Disorder, Nervous System
  3. stem cells Phase 1 · First People's Hospital · Diminished Ovarian Response

Related & competitor drugs

  1. aflibercept Sensory organs (S01)
  2. atropine sulfate Sensory organs (S01)
  3. bimatoprost Sensory organs (S01)
  4. atropine Sensory organs (S01)
  5. brinzolamide Sensory organs (S01)
  6. latanoprost Sensory organs (S01)

Frequently asked questions

What is ex vivo expanded autologous human corneal epithelial cells containing stem cells?

ex vivo expanded autologous human corneal epithelial cells containing stem cells (HOLOCLAR) is a somatic cell supplemental therapy.

What is the brand name for ex vivo expanded autologous human corneal epithelial cells containing stem cells?

HOLOCLAR is a marketed brand name for ex vivo expanded autologous human corneal epithelial cells containing stem cells. Check FDA Drugs@FDA for the current US label holder and prescribing information.