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Drug profile · INN

etirinotecan pegol

ONZEALD

etirinotecan pegol (ONZEALD) is a dna topoisomerase i inhibitor. Associated with Nektar Therapeutics UK Limited.

EMA: refused Antineoplastic and immunomodulating agents (L01) L01
Patents linked 20
Pipeline programs 2
News articles 0
Drug details — etirinotecan pegol
Class
Antineoplastic and immunomodulating agents (L01)
Route
—
Patents
20
Programs
2
Data quality
0.89
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Quick answer

etirinotecan pegol (ONZEALD) is a dna topoisomerase i inhibitor. Associated with Nektar Therapeutics UK Limited.

Key facts

INN etirinotecan pegol
Brand ONZEALD
Mechanism DNA topoisomerase I inhibitor
Target DNA topoisomerase 1
Therapeutic class Antineoplastic and immunomodulating agents (L01)
ATC code L01
Originator Nektar Therapeutics UK Limited

Mechanism of action

DNA topoisomerase I inhibitor

Primary target: DNA topoisomerase 1

Approval history

Authority Status Date
EMA refused —

Pipeline programs

Search pipeline Sponsor programs
  1. IRINOTECAN Phase 3 · COLLEGIUM PHARMACEUTICAL · Gastric Carcinoma
  2. Etirinotecan pegol Phase 2 · Nektar Therapeutics UK · Anaplastic Astrocytomas

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Related patents

Browse patents Nektar Therapeutics UK Limited patent hub

  1. US 12324828

    Conjugates of a factor VIII moiety having an oxime-containing linkage

    Expires Mon Jun 05 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  2. US 12247059

    Conjugates of an IL-2 moiety and a polymer

    Expires Mon Mar 06 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  3. US 12016952

    Methods of preparing a monodisperse oligo(ethylene glycol) reagent composition

    Expires Mon Jun 20 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  4. US 11932726

    Method of making releasable polymeric reagents

    Expires Mon Mar 14 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  5. US 11834553

    Alkoxylation methods

    Expires Mon Nov 30 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  6. US 11672776

    Multi-arm polymeric alkanoate conjugates

    Expires Mon Jun 08 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  7. US 11634540

    Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugation method

    Expires Mon Apr 20 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  8. US 11628205

    Conjugates of a factor VIII moiety having an oxime-containing linkage

    Expires Mon Apr 13 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  9. US 11266742

    Conjugates having a degradable linkage and polymeric reagents useful in preparing such conjugates

    Expires Mon Mar 03 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  10. US 11220575

    Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugation method

    Expires Mon Jan 06 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  11. US 11141465

    Method of making a water-soluble polymer-factor VIII moiety conjugate

    Expires Mon Oct 07 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  12. US 11111214

    Kappa opioid agonists and uses thereof

    Expires Mon Sep 02 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  13. US 11111335

    Method of preparing carboxylic acid functionalized polymers

    Expires Mon Sep 02 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  14. US 11033631

    Methods of treating CYP2D6 alternative metabolizers

    Expires Mon Jun 10 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  15. US 11007270

    Polymer-semaxanib moiety conjugates

    Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  16. US 10960079

    Conjugates of an IL-2 moiety and a polymer

    Expires Mon Mar 25 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  17. US 10945972

    Particulate materials

    Expires Mon Mar 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  18. US 10881738

    Oligomer-beta blocker conjugates

    Expires Mon Dec 31 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  19. US 10869933

    Oligomer-phenothiazine conjugates

    Expires Mon Dec 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  20. US 10865186

    Opioid agonists and uses thereof

    Expires Mon Dec 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is etirinotecan pegol?

etirinotecan pegol (ONZEALD) is a dna topoisomerase i inhibitor. Associated with Nektar Therapeutics UK Limited.

What is the brand name for etirinotecan pegol?

ONZEALD is a marketed brand name for etirinotecan pegol. Check FDA Drugs@FDA for the current US label holder and prescribing information.

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