Friday, July 10, 2026

Drug profile · INN

enfortumab vedotin

enfortumab vedotin (PADCEV) is a tubulin inhibitor. Associated with Astellas Pharma Inc.

EMA: approved TGA: approved Antineoplastic and immunomodulating agents (L01) L01FX13
Patents linked 0
Pipeline programs 14
News articles 1
Drug details — enfortumab vedotin

Quick answer

enfortumab vedotin (PADCEV) is a tubulin inhibitor. Associated with Astellas Pharma Inc.

Key facts

INN enfortumab vedotin
Brand PADCEV
Mechanism Tubulin inhibitor
Target Nectin-4
Therapeutic class Antineoplastic and immunomodulating agents (L01)
ATC code L01FX13

Mechanism of action

Tubulin inhibitor

Primary target: Nectin-4

Approval history

Authority Status Date
EMA approved
TGA approved

Recent coverage

Pipeline programs

  1. 7465-CL-0301 Phase 3 · Astellas Pharma · Locally advanced or metastatic urothelial cancer
  2. D910PC00001 - Volga Phase 3 · AstraZeneca · Bladder Cancer
  3. J4G-MC-JZVD Phase 3 · Eli Lilly and · Carcinoma, Transitional Cell, Urinary Bladder Neoplasms, Neo
  4. MK-3475-905 Phase 3 · MSD Merck Sharp · Muscle Invasive Bladder Cancer
  5. MK3475-B15 Phase 3 · MSD Merck Sharp · Muscle Invasive Bladder Cancer
  6. Enfortumab vedotin Phase 2 · United Therapeutics Europe · Metastatic Urothelial Carcinoma
  7. GEM 2303 Phase 2 · Disc Medicine · Advanced Melanoma
  8. IMMU-132-06 Phase 2 · Gilead Sciences · Locally Advanced/Metastatic Urothelial Cancer

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. axitinib Antineoplastic and immunomodulating agents (L01)
  6. azacitidine Antineoplastic and immunomodulating agents (L01)

Frequently asked questions

What is enfortumab vedotin?

enfortumab vedotin (PADCEV) is a tubulin inhibitor. Associated with Astellas Pharma Inc.

What is the brand name for enfortumab vedotin?

PADCEV is a marketed brand name for enfortumab vedotin. Check FDA Drugs@FDA for the current US label holder and prescribing information.