Friday, July 10, 2026

Drug profile · INN

elacestrant

elacestrant (ORSERDU) is a estrogen receptor alpha degrader.

EMA: approved Antineoplastic and immunomodulating agents (L02) L02BA
Patents linked 0
Pipeline programs 10
News articles 0
Drug details — elacestrant
Class
Antineoplastic and immunomodulating agents (L02)
Route
Patents
0
Programs
10
Data quality
0.83

Quick answer

elacestrant (ORSERDU) is a estrogen receptor alpha degrader.

Key facts

INN elacestrant
Brand ORSERDU
Mechanism Estrogen receptor alpha degrader
Target Estrogen receptor
Therapeutic class Antineoplastic and immunomodulating agents (L02)
ATC code L02BA

Mechanism of action

Estrogen receptor alpha degrader

Primary target: Estrogen receptor

Approval history

Authority Status Date
EMA approved

Pipeline programs

  1. MEDOPP545 Phase 3 · Stemline Therapeutics (United · patients with estrogen receptor-positive/human epidermal gro
  2. STML-ELA-0422 Phase 3 · Stemline Therapeutics (United · Node-positive, Estrogen Receptor-positive, HER2-negative, Ea
  3. ABCSG 63 Phase 2 · Shanghai Zerun Biotechnology · endocrine-responsive HER2-negative early breast cancer
  4. CSET 2025/4053 Phase 2 · George Institute for · Breast cancer
  5. ELA-0121 Phase 2 · Stemline Therapeutics (United · Brain Metastasis from Estrogen Receptor Positive, HER-2 Nega
  6. ELACESTRANT Phase 2 · Telethon Foundation · Patients with HR-positive, HER2-negative, non-metastatic nod
  7. EP0062-101 Phase 2 · Anaxis Pharma · Breast Cancer
  8. Elacestrant Phase 2 · Context Therapeutics · Breast Cancer

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. axitinib Antineoplastic and immunomodulating agents (L01)
  6. azacitidine Antineoplastic and immunomodulating agents (L01)

Frequently asked questions

What is elacestrant?

elacestrant (ORSERDU) is a estrogen receptor alpha degrader.

What is the brand name for elacestrant?

ORSERDU is a marketed brand name for elacestrant. Check FDA Drugs@FDA for the current US label holder and prescribing information.