Friday, July 10, 2026

Drug profile · INN

efgartigimod alfa

efgartigimod alfa (VYVGART) is a igg receptor fcrn large subunit p51 antagonist. Route of administration: injection. Current US regulatory status: approved.

FDA: approved EMA: approved PMDA: approved Antineoplastic and immunomodulating agents (L04) L04AA58
US status approved
Patents linked 0
Pipeline programs 12
News articles 0
Drug details — efgartigimod alfa
US status
approved
Class
Antineoplastic and immunomodulating agents (L04)
Route
INJECTION
Patents
0
Programs
12
Data quality
0.84

Quick answer

efgartigimod alfa (VYVGART) is a igg receptor fcrn large subunit p51 antagonist. Route of administration: injection. Current US regulatory status: approved.

Key facts

INN efgartigimod alfa
Brand VYVGART
Mechanism IgG receptor FcRn large subunit p51 antagonist
Target IgG receptor FcRn large subunit p51
Therapeutic class Antineoplastic and immunomodulating agents (L04)
Route INJECTION
Formulation INJECTABLE
ATC code L04AA58

Mechanism of action

IgG receptor FcRn large subunit p51 antagonist

Primary target: IgG receptor FcRn large subunit p51

Approval history

Authority Status Date
FDA approved
EMA approved
PMDA approved

Pipeline programs

  1. ARGX-113-2008 Phase 3 · Argenx · Generalized Myasthenia Gravis
  2. ARGX-113-2306 Phase 3 · Argenx · Primary Sjögren’s Disease
  3. ARGX-113-2308 Phase 3 · Argenx · Acetylcholine Receptor Binding Antibody Seronegative General
  4. ARGX-113-2309 Phase 3 · Argenx · Thyroid Eye Disease (TED)
  5. ARGX-113-2315 Phase 3 · Argenx · Ocular Myasthenia Gravis
  6. ARGX-113-2402 Phase 3 · Argenx · Primary Immune thrombocytopenia (ITP)
  7. EFGARTIGIMOD ALFA, JNJ-80202135 Phase 3 · Janssen-Cilag International N.V · generalized myasthenia gravis
  8. Vyvgart 1 000 mg solution for injection Phase 3 · Argenx · Generalized Myasthenia Gravis

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. axitinib Antineoplastic and immunomodulating agents (L01)
  6. azacitidine Antineoplastic and immunomodulating agents (L01)

Frequently asked questions

What is efgartigimod alfa?

efgartigimod alfa (VYVGART) is a igg receptor fcrn large subunit p51 antagonist. Route of administration: injection. Current US regulatory status: approved.

What is the brand name for efgartigimod alfa?

VYVGART is a marketed brand name for efgartigimod alfa. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of efgartigimod alfa?

efgartigimod alfa has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.